Empfehlungen basierend auf "The End of Illness"

It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan?In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.”This book takes us to the frontlines of research many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it.

'Ground-breaking. Everyone should read this book' Bessel van der Kolk, author of The Body Keeps the ScoreWhen it comes to understanding the connection between our mental and physical health, we should be looking at the exceptions, not the rules.Dr Jeff Rediger, a world-leading Harvard psychiatrist, has spent the last fifteen years studying thousands of individuals from around the world, examining the stories behind extraordinary cases of recovery from terminal illness.Observing the common denominators of people who have beaten the odds, Dr Rediger reveals the immense power of our immune system and unlocks the secrets of the mind-body connection. In Cured, he explains the vital role that nutrition plays in boosting our immunity and fighting off disease, and he also outlines how stress, trauma and identity affect our physical health.In analysing the remarkable science of recovery, Dr Rediger reveals the power of our mind to heal our body and shows us the keys to good health.'In an era of incurable chronic diseases causing 60% of all deaths worldwide, this book provides one potential way out' Dr Mark Hyman, author of The Blood Sugar Solution'Seasoned with the author's penetrating insights about healing, clearly articulated science and illuminating case histories, Cured opens genuine vistas of transforming illness into health' Gabor Maté, author of When the Body Says No

Reader-friendly Cell Biology, 4th Edition, provides a concise but comprehensive foundation for students entering research or health care career paths. Award winning illustrations help readers quickly grasp general principles. The authors have thoroughly updated this popular text to provide readers with the current understanding of the principles of normal cellular function along with examples of how molecular defects predispose to human disease. Major new themes in the 4th edition include the roles of intrinsically disordered polypeptides and phase separation in cellular functions, the influence of new molecular structures on understanding mechanisms, and the impact of exciting new methods―from single cell RNA sequencing to second generation super resolution fluorescence microscopy―on advancing our understanding.Clear, readable explanations provide a concise story about how cells function at the molecular level.An intuitive chapter flow starts with genome organization, gene expression, and RNA processing as a foundation for understanding every aspect of cellular function and physiology.Brings cellular biology to life for students interested in medical science by explaining how mutations in genes can compromise virtually every cellular system and predispose to human disease. Knowledge of cell biology has led to new treatments for cancer, heart failure, cystic fibrosis, and many other diseases.Unique illustrations with realistic proportions and relationships explain every cellular process including the assembly of SARS CoV-2, the structures attaching mitotic chromosomes to microtubules, the mechanism of DNA replication and how pumps, carriers and channels orchestrate physiological processes from synaptic transmission to cellular volume regulation.Covers exciting breakthroughs such as SMC motor proteins actively organizing chromosomal DNA, TOR kinases regulating metabolism, new types of immunotherapy for cancer treatment, mechanisms regulating fast axonal transport and their relation to neurodegenerative diseases, how completion of DNA replication sets the time for cells to enter mitosis, how a cascade of signals specifies the site of cell division, and newly understood pathways of normal and pathological cell death.Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

A riveting medical mystery about a young woman’s quest to uncover the truth about her likely fatal genetic disorder that opens a window onto the exploding field of genomic medicine When Joselin Linder was in her twenties her legs suddenly started to swell. After years of misdiagnoses, doctors discovered a deadly blockage in her liver. Struggling to find  an explanation for her unusual condition, Joselin compared the medical chart of her father—who had died from a mysterious disease, ten years prior—with that of an uncle who had died under similarly strange circumstances. Delving further into the past, she discovered that her great-grandmother had displayed symptoms similar to hers before her death. Clearly, this was more than a fluke. Setting out to build a more complete picture of the illness that haunted her family, Joselin approached Dr. Christine Seidman, the head of a group of world-class genetic researchers at Harvard Medical School, for help. Dr. Seidman had been working on her family’s case for twenty years and had finally confirmed that fourteen of Joselin’s relatives carried something called a private mutation—meaning that they were the first known people to experience the baffling symptoms of a brand new genetic mutation. Here, Joselin tells the story of their gene: the lives it claimed and the future of genomic medicine with the potential to save those that remain.  Digging into family records and medical history, conducting interviews with relatives and friends, and reflecting on her own experiences with the Harvard doctor, Joselin pieces together the lineage of this deadly gene to write a gripping and unforgettable exploration of family, history, and love. A compelling chronicle of survival and perseverance, The Family Gene is an important story of a young woman reckoning with her father’s death, her own mortality, and her ethical obligations to herself and those closest to her.

If it weren't for mitochondria, scientists argue, we'd all still be single-celled bacteria. Indeed, these tiny structures inside our cells are important beyond imagining. Without mitochondria, we would have no cell suicide, no sculpting of embryonic shape, no sexes, no menopause, no aging.In this fascinating and thought-provoking book, Nick Lane brings together the latest research in this exciting field to show how our growing insight into mitochondria has shed light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. These findings are of fundamental importance, both in understanding life on Earth, but also in controlling our own illnesses, and delaying our degeneration and death. Readers learn that two billion years ago, mitochondria were probably bacteria living independent lives and that their capture within larger cells was a turning point in the evolution of life, enabling the development of complex organisms. Lane describes how mitochondria have their own DNA and that its genes mutate much faster than those in the nucleus. This high mutation rate lies behind our aging and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer. We also discover that mitochondrial DNA is passed down almost exclusively via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to "Mitochondrial Eve," giving us vital information about our evolutionary history.Written by Nick Lane, a rising star in popular science, Power, Sex, Suicide is the first book for general readers on the nature and function of these tiny, yet fascinating structures.

For nearly 40 years, Rosen’s Emergency Medicine has provided emergency physicians, residents, physician assistants, and other emergency medicine practitioners with authoritative, accessible, and comprehensive information in this rapidly evolving field. The fully revised 10th Edition delivers practical, evidence-based knowledge and specific recommendations from clinical experts in a clear, precise format, with focused writing, current references, and extensive use of illustrations to provide definitive guidance for emergency conditions. With coverage ranging from airway management and critical care through diagnosis and treatment of virtually every emergency condition, from highly complex to simple and common, this award-winning, two-volume reference remains your #1 choice for reliable, up-to-date information across the entire spectrum of emergency medicine practice. Offers the most immediately clinically relevant content of any emergency medicine resource, providing diagnostic and treatment recommendations and workflows with clear indications and preferred actions.  Contains eight entirely new chapters covering coronaviruses/COVID-19, the morbidly obese patient, human trafficking, sexual minority (LGBTQ) patients, social determinants of health, community violence, and humanitarian aid in war and crisis.   Features over 1,700 figures, including more than 350 new anatomy drawings, graphs and charts, algorithms, and photos.  Includes new information across the spectrum of emergency care, such as adult and pediatric airway management, shock, pandemic disease, emergency toxicology, sepsis syndrome, resuscitation, medical emergencies of pregnancy, the immunocompromised patient, child abuse, pediatric sedation, pediatric trauma, and more.  Features revised and refined chapter templates that enhance navigation, making it easy to find key information quickly.  Provides access to more than 1,200 questions and answers online to aid in exam preparation, as well as two dozen new video clips showing how to best perform critical emergency procedures in real time.  Reviewed and verified cover-to-cover by a team of expert clinical pharmacists to ensure accuracy and completeness of all drug information and treatment recommendations. 

Gold Award Winner, 2024 Nonfiction Book Awards Runner-up, 2024 History category, San Francisco Book Festival Runner-up, 2024 General Non-Fiction, New York Book Festival For much of recorded history, people considered the heart to be the most important organ in the body. In cultures around the world, the heart—not the brain—was believed to be the location of intelligence, memory, emotion, and the soul. Over time, views on the purpose of the heart have transformed as people sought to understand the life forces it contains. Modern medicine and science dismissed what was once the king of the organs as a mere blood pump subservient to the brain, yet the heart remains a potent symbol of love and health and an important part of our cultural iconography. This book traces the evolution of our understanding of the heart from the dawn of civilization to the present. Vincent M. Figueredo—an accomplished cardiologist and expert on the history of the human heart—explores the role and significance of the heart in art, culture, religion, philosophy, and science across time and place. He examines how the heart really works, its many meanings in our emotional and daily lives, and what cutting-edge science is teaching us about this remarkable organ. Figueredo considers the science of heart disease, recent advancements in heart therapies, and what the future may hold. He highlights the emerging field of neurocardiology, which has found evidence of a “heart-brain connection” in mental and physical health, suggesting that ancient views hold more truth than moderns suspect. Ranging widely and deeply throughout human history, this book sheds new light on why the heart remains so central to our sense of self.

SHORTLISTED FOR THE COSTA BIOGRAPHY PRIZE THE SUNDAY TIMES NO.2 BESTSELLER WINNER OF THE BMA PRESIDENT'S AWARD 2017 An incredible memoir from one of the world's most eminent heart surgeons, recalling some of the most remarkable and poignant cases he's worked on. Grim Reaper sits on the heart surgeon's shoulder. A slip of the hand and life ebbs away. The balance between life and death is so delicate, and the heart surgeon walks that rope between the two. In the operating room there is no time for doubt. It is flesh, blood, rib-retractors and pumping the vital organ with your bare hand to squeeze the life back into it. An off-day can have dire consequences - this job has a steep learning curve, and the cost is measured in human life. Cardiac surgery is not for the faint of heart. Professor Stephen Westaby took chances and pushed the boundaries of heart surgery. He saved hundreds of lives over the course of a thirty-five year career and now, in his astounding memoir, Westaby details some of his most remarkable and poignant cases - such as the baby who had suffered multiple heart attacks by six months old, a woman who lived the nightmare of locked-in syndrome, and a man whose life was powered by a battery for eight years. A powerful, important and incredibly moving book, Fragile Lives offers an exceptional insight into the exhilarating and sometimes tragic world of heart surgery, and how it feels to hold someone's life in your hands.

From the international bestselling author of Gut, an entertaining and highly informative book about how the body's organs work in tandem to keep us as healthy as we can be. In a world that is becoming ever louder and more complex, sometimes the best perspective is to look inward--at our own physicality. For thousands of years, our bodies have faced challenges and found their own unique ways to overcome them. What can we learn from these extraordinarily complex beings? In her new book, internationally renowned medical expert and star of Netflix's Hack Your Health Giulia Enders embarks on a journey of discovery into our inner workings, raising fundamental questions: What can the immune system teach us about security? How does the process of wound-healing inform our understanding of emotional recovery? What do we truly need to thrive? What are we capable of when we achieve peak health? How do we truly want to treat one another? Our bodies offer fascinating answers to all these questions, transforming our perspective on life itself. With the latest scientific insights and her unmatched talent for making complex concepts vividly accessible, Giulia Enders inspires a deep appreciation for something that is both intimately familiar yet profoundly mysterious--the very basis for how we find our happiest selves.

No matter what you eat, how much you exercise, how skinny or young or wise you are, none of it matters if you're not breathing properly. There is nothing more essential to our health and wellbeing than breathing- take air in, let it out, repeat 25,000 times a day. Yet, as a species, humans have lost the ability to breathe correctly, with grave consequences. Journalist James Nestor travels the world to figure out what went wrong and how to fix it. The answers aren't found in pulmonology labs, as we might expect, but in the muddy digs of ancient burial sites, secret Soviet facilities, New Jersey choir schools, and the smoggy streets of S o Paulo, Brazil. Nestor tracks down men and women exploring the hidden science behind ancient breathing practices like Pranayama, Sudarshan Kriya and Tummo and teams up with pulmonary tinkerers to scientifically test longheld beliefs about how we breathe. Modern research is showing us that making even slight adjustments to the way we inhale and exhale can jump-start athletic performance, rejuvenate internal organs, halt snoring, allergies, asthma and autoimmune disease, and even straighten scoliotic spines. None of this should be possible, and yet it is. Drawing on thousands of years of medical texts and recent cutting-edge studies in pulmonology, psychology, biochemistry and human physiology, Breath turns the conventional wisdom of what we thought we knew about our most basic biological function on its head. You will never breathe the same again.