Empfehlungen basierend auf "Molecular Biology of Cancer Mechanisms, Targets, and Therapeutics"

In this paradigm-shifting book from acclaimed Harvard Medical School doctor and one of TIME magazine's 100 most influential people on earth, Dr. David Sinclair reveals that everything we think we know about ageing is wrong, and shares the surprising, scientifically-proven methods that can help readers live younger, longer. For decades, the medical community has looked to a variety of reasons for why we age, and the consensus is that no one dies of old age; they die of age-related diseases. That's because ageing is not a disease - it is inevitable.But what if everything you think you know about ageing is wrong?What if ageing is a disease? And that disease is curable.In THE EVOLUTION OF AGEING, Dr. David Sinclair, one of the world's foremost authorities on genetics and ageing, argues just that. He has dedicated his life's work to chasing more than a longer lifespan - he wants to enable people to live longer, healthier, and disease-free well into our hundreds. In this book, he reveals a bold new theory of ageing, one that pinpoints a root cause of ageing that lies in an ancient genetic survival circuit. This genetic trick - a circuit designed to halt reproduction in order to repair damage to the genome -has enabled earth's early microcosms to survive and evolve into more advanced organisms. But this same survival circuit is the reason we age: as genetic damage accumulates over our lifespans from UV rays, environmental toxins, and unhealthy diets, our genome is overwhelmed, causing gray hair, wrinkles, achy joints, heart issues, dementia, and, ultimately, death.But genes aren't our destiny; we have more control over them than we've been taught to believe. We can't change our DNA, but we can harness the power of the epigenome to realise the true potential of our genes. Drawing on his cutting-edge findings at the forefront of medical research, Dr. Sinclair will provide a scientifically-proven roadmap to reverse the genetic clock by activating our vitality genes, so we can live younger longer. Readers will discover how a few simple lifestyle changes - like intermittent fasting, avoiding too much animal protein, limiting sugar, avoiding x-rays, exercising with the right intensity, and even trying cold therapy - can activate our vitality genes. Dr. Sinclair ends the book with a look to the near future, exploring what the world might look like - and what will need to change - when we are all living well to 120 or more.Dr. Sinclair takes what we have long accepted as the limits of human potential and mortality and turns them into choices. THE EVOLUTION OF AGEING is destined to be the biggest book on genes, biology, and longevity of this decade.

"While we accept that stress or anxiety can damage our health, the idea of 'healing thoughts' was long ago hijacked by New Age gurus and spiritual healers. Recently, however, serious scientists ... have been uncovering evidence that our thoughts, emotions, and beliefs can ease pain, heal wounds, fend off infection and heart disease, even slow the progression of AIDS and some cancers. In [this book], ... Marchant travels the world to meet the physicians, patients, and researchers on the cutting edge of this new world of medicine. We learn how meditation protects against depression and dementia, how social connections increase life expectancy, and how patients who feel cared for recover from surgery faster"--

A NEW YORK TIMES BESTSELLERFrom a renowned behavioral neuroscientist and recovering addict, a rare page-turning work of science that draws on personal insights to reveal how drugs work, the dangerous hold they can take on the brain, and the surprising way to combat today's epidemic of addiction.Judith Grisel was a daily drug user and college dropout when she began to consider that her addiction might have a cure, one that she herself could perhaps discover by studying the brain. Now, after twenty-five years as a neuroscientist, she shares what she and other scientists have learned about addiction, enriched by captivating glimpses of her personal journey.In Never Enough, Grisel reveals the unfortunate bottom line of all regular drug use: there is no such thing as a free lunch. All drugs act on the brain in a way that diminishes their enjoyable effects and creates unpleasant ones with repeated use. Yet they have their appeal, and Grisel draws on anecdotes both comic and tragic from her own days of using as she limns the science behind the love of various drugs, from marijuana to alcohol, opiates to psychedelics, speed to spice.With more than one in five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide, and Grisel delves with compassion into the science of this scourge. She points to what is different about the brains of addicts even before they first pick up a drink or drug, highlights the changes that take place in the brain and behavior as a result of chronic using, and shares the surprising hidden gifts of personality that addiction can expose. She describes what drove her to addiction, what helped her recover, and her belief that a “cure” for addiction will not be found in our individual brains but in the way we interact with our communities.Set apart by its color, candor, and bell-clear writing, Never Enough is a revelatory look at the roles drugs play in all of our lives and offers crucial new insight into how we can solve the epidemic of abuse.

'The best deep dive into the diseases that plague us all today, and what to do to heal.' Jessie Inchauspe, The Glucose Goddess 'Good Energy is a powerful vision for a brighter future – for both people and the planet.' Jay Shetty 'A tour de force' Dr Mark Hyman

For nearly 40 years, Rosen’s Emergency Medicine has provided emergency physicians, residents, physician assistants, and other emergency medicine practitioners with authoritative, accessible, and comprehensive information in this rapidly evolving field. The fully revised 10th Edition delivers practical, evidence-based knowledge and specific recommendations from clinical experts in a clear, precise format, with focused writing, current references, and extensive use of illustrations to provide definitive guidance for emergency conditions. With coverage ranging from airway management and critical care through diagnosis and treatment of virtually every emergency condition, from highly complex to simple and common, this award-winning, two-volume reference remains your #1 choice for reliable, up-to-date information across the entire spectrum of emergency medicine practice. Offers the most immediately clinically relevant content of any emergency medicine resource, providing diagnostic and treatment recommendations and workflows with clear indications and preferred actions.  Contains eight entirely new chapters covering coronaviruses/COVID-19, the morbidly obese patient, human trafficking, sexual minority (LGBTQ) patients, social determinants of health, community violence, and humanitarian aid in war and crisis.   Features over 1,700 figures, including more than 350 new anatomy drawings, graphs and charts, algorithms, and photos.  Includes new information across the spectrum of emergency care, such as adult and pediatric airway management, shock, pandemic disease, emergency toxicology, sepsis syndrome, resuscitation, medical emergencies of pregnancy, the immunocompromised patient, child abuse, pediatric sedation, pediatric trauma, and more.  Features revised and refined chapter templates that enhance navigation, making it easy to find key information quickly.  Provides access to more than 1,200 questions and answers online to aid in exam preparation, as well as two dozen new video clips showing how to best perform critical emergency procedures in real time.  Reviewed and verified cover-to-cover by a team of expert clinical pharmacists to ensure accuracy and completeness of all drug information and treatment recommendations. 

As One Of The World's Leading Brain Surgeons, Dr Jandial Is The Last Hope For Many Patients Who Have Extreme Forms Of Cancer - Patients Who Can't Be Saved, But Deserve More Time. Life On A Knife's Edge Is His Account Of The Resilience, Courage And Belief He Has Witnessed In His Patients, And The Lessons He Has Learned From Them. Both An Unflinching Account Of Extreme Surgeries And A Profound, Moving And Introspective Memoir, This Book Reveals The Depths Of A Surgeon's Psyche Who Is Pushed To His Limits, Day In, Day Out. From Keeping A Gun Victim's Heart Pumping With His Own Hand, To Saving A Woman From Paralysis And Performing Brain Surgery While Time Is Running Out On A Haemorrhaging Patient, We See How Making Life And Death Decisions And Facing Unimaginable Pressure Has Shaped One Man's Life. In This Breathtaking Memoir, Dr Jandial Shares What He's Learned About Human Nature, From Balancing The Line Between Life And Death Everyday.

The next time you get sick, consider this before picking up the aspirin: your body may be doing exactly what it's supposed to. In this ground-breaking book, two pioneers of the science of Darwinian medicine argue that illness as well as the factors that predispose us toward it are subject to the same laws of natural selection that otherwise make our bodies such miracles of design.  Among the concerns they raise: When may a fever be beneficial? Why do pregnant women get morning sickness? How do certain viruses "manipulate" their hosts into infecting others? What evolutionary factors may be responsible for depression and panic disorder? Deftly summarizing research on disorders ranging from allergies to Alzheimer's, and form cancer to Huntington's chorea, Why We Get Sick, answers these questions and more.  The result is a book that will revolutionize our attitudes toward illness and will intrigue and instruct lay person and medical practitioners alike.

No matter what you eat, how much you exercise, how skinny or young or wise you are, none of it matters if you're not breathing properly. There is nothing more essential to our health and wellbeing than breathing- take air in, let it out, repeat 25,000 times a day. Yet, as a species, humans have lost the ability to breathe correctly, with grave consequences. Journalist James Nestor travels the world to figure out what went wrong and how to fix it. The answers aren't found in pulmonology labs, as we might expect, but in the muddy digs of ancient burial sites, secret Soviet facilities, New Jersey choir schools, and the smoggy streets of S o Paulo, Brazil. Nestor tracks down men and women exploring the hidden science behind ancient breathing practices like Pranayama, Sudarshan Kriya and Tummo and teams up with pulmonary tinkerers to scientifically test longheld beliefs about how we breathe. Modern research is showing us that making even slight adjustments to the way we inhale and exhale can jump-start athletic performance, rejuvenate internal organs, halt snoring, allergies, asthma and autoimmune disease, and even straighten scoliotic spines. None of this should be possible, and yet it is. Drawing on thousands of years of medical texts and recent cutting-edge studies in pulmonology, psychology, biochemistry and human physiology, Breath turns the conventional wisdom of what we thought we knew about our most basic biological function on its head. You will never breathe the same again.

Published upon the opening of the Wellcome Collection, the Wellcome Trust's new public venue in London, this book examines the history of our understanding of the human heart. Encompassing material from Henry Wellcome's own collections in the Wellcome Library and images and artifacts from private and public archives across the world, the book provides a richly illustrated account of changes in our perception of what the heart does and what it means.The book first explores the symbolic significance of the heart in ancient Egypt, China, India, and Greece; its role in Aztec ceremony; and its place in the medieval world. It then considers the centrality of the heart in Christianity and other religions and the literary and artistic views of the heart as the seat of the soul and emotions.The growth of anatomical knowledge of the heart and its treatment through developing technology is fundamental to the volume. Fifteenth-century drawings by Leonardo da Vinci reveal his extraordinary early insight into the heart's mechanisms, and twentieth-century medical breakthroughs prompt questions about ownership of the heart and the source of life itself. With testimony from surgeons and patients, the book highlights developments in cardiac surgery and considers future alternatives involving gene therapy, stem cell options, and micro-surgery.ContentsLouisa Young: The Human HeartFrancis Wells: The Renaissance HeartEmily Jo Sargent: The Sacred HeartFay Bound Alberti: The Emotional HeartAyesha Nathoo: The Transplanted HeartMelissa Larner: The Healing HeartTed Bianco: The Animal HeartMichael Bracewell: The Broken HeartJon Turney: The Future Heart

'Read this book and you're virtually a qualified doctor! Educational and entertaining - it should be on the national curriculum!'- Harry Hill 'Hilarious and fascinating! I wish Adam had been my biology teacher' - Konnie Huq The brand-new, hilarious book from bestselling, record-breaking author Adam Kay. The olden days were pretty fun if you liked wearing chainmail or chopping people's heads off but there was one TINY LITTLE problem back then . . . doctors didn't have the slightest clue about how our bodies worked. It's time to find out why Ancient Egyptians thought the brain was just a useless load of old stuffing that might as well be chucked in the bin, why teachers forced their pupils to smoke cigarettes, why hairdressers would cut off their customers' legs, and why people used to get paid for farting. (Unfortunately that's no longer a thing - sorry.) You'll get answers to questions like: Why did patients gargle with wee? How did a doctor save people's lives using a washing machine, a can of beans and some old sausages? What was the great stink? (No, it's not what doctors call your bum.) If you're sure you're ready, then pop a peg on your nose (there was a lot of stinky pus back then), pull on your wellies (there was a lot of poo there too), wash your hands (because they certainly didn't) and explore this gross and gruesome history of the human body! Praise for Kay's Anatomy: 'An enjoyably gross look at the human body. Hours of gruesome fun guaranteed' i 'Like listening to a teacher who makes pupils fall about' Sunday Times 'Totally brilliant!' Jacqueline Wilson 'Fun and informative' Malorie Blackman 'Very funny - this exciting book is bound to inspire the next generation of medics' Sunday Express