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A story of courage and risk-taking, House on Fire tells how smallpox, a disease that killed, blinded, and scarred millions over centuries of human history, was completely eradicated in a spectacular triumph of medicine and public health. Part autobiography, part mystery, the story is told by a man who was one of the architects of a radical vaccination scheme that became a key strategy in ending the horrible disease when it was finally contained in India. In House on Fire, William H. Foege describes his own experiences in public health and details the remarkable program that involved people from countries around the world in pursuit of a single objective―eliminating smallpox forever. Rich with the details of everyday life, as well as a few adventures, House on Fire gives an intimate sense of what it is like to work on the ground in some of the world’s most impoverished countries―and tells what it is like to contribute to programs that really do change the world.

If it weren't for mitochondria, scientists argue, we'd all still be single-celled bacteria. Indeed, these tiny structures inside our cells are important beyond imagining. Without mitochondria, we would have no cell suicide, no sculpting of embryonic shape, no sexes, no menopause, no aging.In this fascinating and thought-provoking book, Nick Lane brings together the latest research in this exciting field to show how our growing insight into mitochondria has shed light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. These findings are of fundamental importance, both in understanding life on Earth, but also in controlling our own illnesses, and delaying our degeneration and death. Readers learn that two billion years ago, mitochondria were probably bacteria living independent lives and that their capture within larger cells was a turning point in the evolution of life, enabling the development of complex organisms. Lane describes how mitochondria have their own DNA and that its genes mutate much faster than those in the nucleus. This high mutation rate lies behind our aging and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer. We also discover that mitochondrial DNA is passed down almost exclusively via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to "Mitochondrial Eve," giving us vital information about our evolutionary history.Written by Nick Lane, a rising star in popular science, Power, Sex, Suicide is the first book for general readers on the nature and function of these tiny, yet fascinating structures.

This book is about the discovery that the human brain has its own unique way of healing. For centuries we believed that the price we paid for our brain’s complexity was that, compared to other organs, it was fixed and unregenerative — unable to recover from damage or illness. In his revolutionary new book, Norman Doidge turns this belief on its head.The phenomenon of neuroplasticity — the discovery that the brain can change its own structure and function in response to mental experience — is the most important development in our understanding of the brain and mind since the beginning of modern science. Here, Doidge shows how the amazing process of neuroplastic healing really works. When it is understood, it is often possible to radically improve — and even cure — many conditions thought to be irreversible.Doidge introduces us to the doctors, therapists, and patients who are healing the brain without surgery or medication. We meet patients who have alleviated years of chronic pain; children on the autistic spectrum, or with ADD or learning disorders, who have used neuroplastic techniques to complete a normal education and become independent; and sufferers who have seen symptoms of multiple sclerosis, Parkinson’s disease, brain injuries, and cerebral palsy radically diminish; and we learn how to lower our risk of dementia by 60 per cent. Through hopeful, astonishing stories, The Brain’s Way of Healing explains how mind, brain, and body, and the energies around us, work together in health and healing.

Journalist Beth Macy's definitive account of America's opioid epidemic "masterfully interlaces stories of communities in crisis with dark histories of corporate greed and regulatory indifference" (New York Times) -- from the boardroom to the courtroom and into the living rooms of Americans.In this extraordinary work, Beth Macy takes us into the epicenter of a national drama that has unfolded over two decades. From the labs and marketing departments of big pharma to local doctor's offices; wealthy suburbs to distressed small communities in Central Appalachia; from distant cities to once-idyllic farm towns; the spread of opioid addiction follows a tortuous trajectory that illustrates how this crisis has persisted for so long and become so firmly entrenched.Beginning with a single dealer who lands in a small Virginia town and sets about turning high school football stars into heroin overdose statistics, Macy sets out to answer a grieving mother's question-why her only son died-and comes away with a gripping, unputdownable story of greed and need. From the introduction of OxyContin in 1996, Macy investigates the powerful forces that led America's doctors and patients to embrace a medical culture where overtreatment with painkillers became the norm. In some of the same communities featured in her bestselling book Factory Man, the unemployed use painkillers both to numb the pain of joblessness and pay their bills, while privileged teens trade pills in cul-de-sacs, and even high school standouts fall prey to prostitution, jail, and death.Through unsparing, compelling, and unforgettably humane portraits of families and first responders determined to ameliorate this epidemic, each facet of the crisis comes into focus. In these politically fragmented times, Beth Macy shows that one thing uniting Americans across geographic, partisan, and class lines is opioid drug abuse. But even in the midst of twin crises in drug abuse and healthcare, Macy finds reason to hope and ample signs of the spirit and tenacity that are helping the countless ordinary people ensnared by addiction build a better future for themselves, their families, and their communities."An impressive feat of journalism, monumental in scope and urgent in its implications." -- Jennifer Latson, The Boston Globe

Describes the search for the genes that control cancer, explains the difficulties of research in molecular biology, and assesses progress towards a more detailed understanding of cancer

While it may seem that debates over euthanasia began with Jack Kervorkian, the practice of mercy killing extends back to Ancient Greece and beyond. In America, the debate has raged for well over a century. Now, in A Merciful End, Ian Dowbiggin offers the first full-scale historical account of one of the most controversial reform movements in America. Drawing on unprecedented access to the archives of the Euthanasia Society of America, interviews with important figures in the movement today, and flashpoint cases such as the tragic fate of Karen Ann Quinlan, Dowbiggin tells the dramatic story of the men and women who struggled throughout the twentieth century to change the nation's attitude--and its laws--regarding mercy killing. In tracing the history of the euthanasia movement, he documents its intersection with other progressive social causes: women's suffrage, birth control, abortion rights, as well as its uneasy pre-WWII alliance with eugenics. Such links brought euthanasia activists into fierce conflict with Judeo-Christian institutions who worried that "the right to die" might become a "duty to die." Indeed, Dowbiggin argues that by joining a sometimes overzealous quest to maximize human freedom with a desire to "improve" society, the euthanasia movement has been dogged by the fear that mercy killing could be extended to persons with disabilities, handicapped newborns, unconscious geriatric patients, lifelong criminals, and even the poor. Justified or not, such fears have stalled the movement, as more and more Americans now prefer better end-of-life care than wholesale changes in euthanasia laws. For anyone trying to decide whether euthanasia offers a humane alternative to prolonged suffering or violates the "sanctity of life," A Merciful End provides fascinating and much-needed historical context.

From a leading neuroscientist and practitioner of Ayurvedic medicine, rigorous scientific investigation of sound as energy frequency, showing readers how to use its powers for healing and wellness.Why does a baby’s cry instantaneously flood a mother’s body with a myriad of stress hormones? How can a song on the radio stir up powerful emotions, from joy to anger, regret to desire? Why does sound itself evoke such primal and deeply felt feelings?A vibration that travels through air, water and solids, sound is produced by all matter, and is a fundamental part of every species’ survival. But there is a hidden power within sound that has yet to be investigated by modern medicine. Sound Medicine takes readers on a journey through the structure of the mouth, ears, and brain to understand how sound is translated from acoustic vibrations into meaningful neurological impulses. Renowned neuroscientist and Aryuvedic expert Dr. Kulreet Chaudrahy explains how different types of sound impact the human body and brain uniquely, and explores the physiological effects of sound vibration, from altering mood to healing disease.Blending ancient wisdom and modern science, Dr. Choudry traces the history of sound therapy and the use of specific mantras from ancient Aryuvedic texts, to explain the biology of sound as frequency and its therapeutic applications for common ailments. Sound Medicine offers practical, step-by-step lessons for using music and mantras, whether you’re a beginner or searching for a more advanced practice. Bringing together Vedic mythology and medical therapy, this marriage of the ancient mantras and modern neuroscience can help you heal—and keep you well in body, mind, and spirit.

Cure Your Food Cravings Once and For AllIf sweets and high-fat foods are sabotaging your efforts to lose weight and get healthy, Dr. Neal Barnard has the solution to conquering your food addictions. Backed up by scientific research, Breaking the Food Seduction explains that your biochemistry, not your lack of willpower, is the problem. Dr. Barnard reveals the simple dietary and lifestyle changes that can break the stubborn cycle of cravings and make you free to choose healthy and tasty foods that can help to you lose weight, lower cholesterol, and improve your overall health.Featuring a 3-week kickstart plan and 100 delicious, satisfying recipes

The word concussion used to be unheard of in youth sports a decade ago. The brain injury was indeed occurring, but coaches and parents were encouraging their youth athletes to "shake it off" after "getting their bell rung". Science and increased awareness about concussion are transforming the way youth parents, coaches, and players pursue athletics. Fear of incurring concussions, as well as incorrect information, is leading some parents to keep their children out of contact sports, such as football and soccer, where concussion is more prevalent.Back in the Game: Why Concussion Doesn't Have to End Your Athletic Career does not dwell on perpetuating fears, but rather, provides the most up-to-date understanding of the condition. This text includes a real-world discussion of what science and medicine knows, what parents and coaches need to understand about concussions, evaluation and treatment, and possible post-concussive issues, like depression. At the heart of this book, the authors delve into these issues, explaining them in a clear and understandable way.The expertise and experiences of noted sports neurologist Jeffrey Kutcher, MD, along with reporting and interviews by award-winning sports journalist Joanne C. Gerstner, makes this book a timely, relevant, and real discussion about concussions in youth sports. Athletes and professional coaches who have participated in the formation of this book include two-time Olympic gold medalist soccer player Kate Markgraf, former NHL/Team Canada head coach Andy Murray, champion X-Games snowboarder Ellery Hollingsworth, along with an array of youth parents, coaches, and athletes from across the country.

International Bestseller —Translated into 15 Languages"This is a most important book, both for patient and physician. It could save your life." — Peter Levine, PhD, best selling author of In an Unspoken Voice"Gabor Maté, M.D., skillfully blends recent advances in biomedicine with the personal stories of his patients to provide empowering insights into how deeply developmental experiences shape our health, behavior, attitudes, and relationships. A must read." ? Bruce Lipton, Ph.D., author of The Biology of BeliefThe international bestseller is a groundbreaking exploration of the effects of the mind-body connection on stress and disease? and how we can heal.Through the lens of moving personal stories, medical doctor and best-selling author Dr.Gabor Maté shows how emotion and psychological stress play a powerful role in the onset of chronic illness, cancer, and many other serious illnesses.Drawing on scientific research and the author's decades of experience as a practicing physician, this book provides answers to important questions about the effect of the mind-body link on illness and health and the role that chronic stress and one's individual emotional makeup play in an array of common diseases. Explore the role of the mind-body link in conditions and diseases such as arthritis, cancer, diabetes, heart disease, IBS, multiple sclerosis, autoimmune conditions, and more The book draws on years of medical research and the author's own clinical experience as a family physician Complete with The Seven A's of Healing – Once you're ready to acknowledge underlying stress, Dr. Mate guides you forward with principles of healing, management, and the prevention of illness from hidden stress Discover dozens of enlightening case studies and personal stories, including familiar names such as Lou Gehrig (ALS), Betty Ford (breast cancer), Ronald Reagan (Alzheimer's), Gilda Radner (ovarian cancer), and Lance Armstrong (testicular cancer) An impressive contribution to research on the physiological connection between life's chronic stress cycles, anxiety, and emotions and the body systems governing nerves, immune apparatus, and hormones