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If it weren't for mitochondria, scientists argue, we'd all still be single-celled bacteria. Indeed, these tiny structures inside our cells are important beyond imagining. Without mitochondria, we would have no cell suicide, no sculpting of embryonic shape, no sexes, no menopause, no aging.In this fascinating and thought-provoking book, Nick Lane brings together the latest research in this exciting field to show how our growing insight into mitochondria has shed light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. These findings are of fundamental importance, both in understanding life on Earth, but also in controlling our own illnesses, and delaying our degeneration and death. Readers learn that two billion years ago, mitochondria were probably bacteria living independent lives and that their capture within larger cells was a turning point in the evolution of life, enabling the development of complex organisms. Lane describes how mitochondria have their own DNA and that its genes mutate much faster than those in the nucleus. This high mutation rate lies behind our aging and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer. We also discover that mitochondrial DNA is passed down almost exclusively via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to "Mitochondrial Eve," giving us vital information about our evolutionary history.Written by Nick Lane, a rising star in popular science, Power, Sex, Suicide is the first book for general readers on the nature and function of these tiny, yet fascinating structures.

“Nicole Jardim walks the talk, and I am confident that Fix Your Period will help ignite the hormone balance you are seeking and restore your vitality.” --Sara Gottfried, MD, New York Times bestselling author of The Hormone CureA life-changing step-by-step natural protocol to ignite lasting hormone balance and improve everything from PMS, period pain, and heavy periods to irregular cycles and missing periods, from Nicole Jardim, certified women’s health coach and co-host of the podcast The Period Party.For most women, getting their period sucks. Bloating. Cramps. Acne. Aches. Moodiness. Messiness. No wonder we call it The Curse! For many, it’s not just an inconvenience—it’s a colossal life disruption, forcing them to miss work, school, appointments, or dates.We’ve been encouraged to medicate away common period problems with birth control and ibuprofen, and just survive the mood swings as best we can. But as Nicole Jardim explains, periods aren’t a nuisance, they’re information. When you learn to decode your period (or lack thereof), you’ll be able to recognize the underlying hormone imbalances causing your period problems and know how to fix them naturally with Jardim’s proven six-week protocol to resolve even the most challenging hormone imbalances and menstruation issues.Joining the ranks of books by Jolene Brighten, Sara Gottfried, and Aviva Romm, Nicole Jardim’s Fix Your Period is essential for women plagued by PMS, irregular, painful, or heavy periods, PCOS, Endometriosis, or fibroids—and for anyone who wants to take charge of her hormonal health—and regain control of her life—naturally.

'Ground-breaking, fascinating, important . . . we were astounded' Deliciously Ella, Delicious Ways to Feel BetterA myth-busting tour of the body's hidden foundations from a pioneering evolutionary biologistOver the past twenty years, evolutionary biologist Herman Pontzer has conducted ground-breaking studies across a range of settings, including pioneering fieldwork with Hadza hunter-gatherers in northern Tanzania.This book draws on his eye-opening research to show how, contrary to received wisdom, exercise does not increase our metabolism. Instead, we burn calories within a very narrow range: nearly 3,000 calories per day, no matter our activity level.By taking a closer look at what happens to the energy we consume, Pontzer explores the ways in which metabolism controls every aspect of our health - from fertility to immune function - and reveals the truth about the dynamic system that sustains us. Filled with facts and memorable anecdotes, Burn will change the way you think about food, exercise and life.

Gifted Hands reveals the remarkable journey of Dr. Ben Carson from an angry, struggling young boy with everything stacked against him to the director of pediatric neurosurgery at the Johns Hopkins Children's Center.As a boy, he did poorly in school and struggled with anger. If it were not for the persistence of his mother, a single parent who worked three jobs and pushed her sons to do their best, his story may have ended tragically.Join Dr. Carson on his journey from a struggling inner-city student to the pinnacle of his career as a world-renowned neurosurgeon. A man of humility, decency, compassion, courage, and sensitivity, he now serves as a role model for everyone who wants to achieve their God-given potential.As you learn more about Dr. Carson's amazing story, you'll be inspired to: Take charge of your own destiny Hone your God-given gifts Face adversity head on Filled with fascinating stories, Gifted Hands will transport you into the operating room to witness surgeries that made headlines around the world, and into the private mind of a compassionate, God-fearing physician who lives to help others.

THE LATEST BOOK FROM THE AUTHOR OF THE SUNDAY TIMES #1 BESTSELLER FEEL BETTER IN 5'This is not a diet book. This is a whole new way of looking at what, why and how we eat and helps you design your own plan to build a better, healthier relationship with food' Fearne Cotton'A book with practical simple tips for everyone!' Tim Spector'It is a beautiful book and has so much in it to help us feel good and prioritise our happiness and health' Dr Gemma Newman'One of the most influential doctors in the country' Chris Evans_________________________________________________________________________It's more important than ever before that we get in shape, stay healthy and live well - Dr Chatterjee is back to show you how.Weight loss isn't a race. It isn't one size fits all. Drawing on twenty years of experience as a GP, Dr Rangan Chatterjee has created a conscious, long-lasting approach to weight loss that goes far beyond fad diets and helps to find the best solutions that work for you. Packed with quick and easy interventions this book will help you:1. Understand the effects of what, why, when, where and how we eat2. Discover the root cause of your weight gain3. Nourish your body without any crash diets or gruelling workouts4. Build a toolbox of techniques to help you lose weight, for goodWith Feel Great, Lose Weight you can make sustainable, medically-approved lifestyle changes and become a more energised, confident and healthy you._________________________________________________________________________'A blame-free book' Telegraph'This book is extremely practical, insightful and easy-to-follow' The Happy Pears

Discover the most important and groundbreaking milestones in the history of medicine, and the people behind them.From ancient herbal remedies to modern drugs, this accessible medical reference book explores the breakthroughs and discoveries that have shaped our modern-day understanding of medicine.Inside the pages of this illustrated medicine history book, you'll discover:- Profiles of more than 90 of the biggest ideas, breakthroughs, and milestones in international medical history- Thought-provoking graphics and flow-charts that demystify the central concepts behind each medical idea- Insightful and inspiring quotes from famous physicians, scientists, politicians, and academicsHow are illnesses diagnosed? How do vaccinations work? Why are some pandemics so deadly?This informative book about medicine through time answers big questions like these and many more!Packed with pithy explanations, step-by-step diagrams and bright illustrations, The Medicine Book cuts through the jargon and offers a clear overview of the greatest medical breakthroughs. Learn about major diseases such as cancer and the global eradication of smallpox. Explore new developments in IVF and gene manipulation, as well as medical science's response to global challenges, such as COVID-19.It's perfect for medical professionals, students of medicine, or anyone interested in the fascinating medical history of the world.Complete the series:The Big Ideas Simply Explained series follows an innovative visual approach to make any subject accessible to everyone. Discover more than 100 of the most infamous, audacious, gory, horrifying, and notorious crimes in The Crime Book. Explore more than 90 of the most awe-inspiring astronomical ideas in The Astronomy Book.

An examination of the contemporary medicalization of death and dying that calls us to acknowledge instead death's existential and emotional realities. Death is a natural, inevitable, and deeply human process, and yet Western medicine tends to view it as a medical failure. In their zeal to prevent death, physicians and hospitals often set patients and their families on a seemingly unstoppable trajectory toward medical interventions that may actually increase suffering at the end of life. This volume in the MIT Press Essential Knowledge series examines the medicalization of death and dying and proposes a different approach--one that acknowledges death's existential and emotional realities. The authors--one an academic who teaches and studies end-of-life care, and the other a physician trained in hospice and palliative care--offer an account of Western-style death and dying that is informed by both research and personal experience. They examine the medical profession's attitude toward death as a biological dysfunction that needs fixing; describe the hospice movement, as well as movements for palliative care and aid in dying, and why they failed to influence mainstream medicine; consider our reluctance to have end-of-life conversations; and investigate the commodification of medicine and the business of dying. To help patients die in accordance with their values, they say, those who care for the dying should focus less on delaying death by any means possible and more on being present with the dying on their journey.

Dr Webster puts a face on chronic pain through describing the lives of patients. 'The Painful Truth' opens readers' eyes to a population who are stigmatized and marginalized by society. Yet the work offers a path forward for those willing to engage in a crusade against our primal enemy: pain.

THE INTERNATIONAL BESTSELLER Best Books of the Year, Guardian The poignant story of the visionary surgeon who rebuilt the faces of the First World War's injured heroes, and in the process ushered in the modern era of plastic surgery From the moment the first machine gun rang out over the Western Front, one thing was clear: mankind's military technology had wildly surpassed its medical capabilities. The war's new weaponry, from tanks to shrapnel, enabled slaughter on an industrial scale, and given the nature of trench warfare, thousands of soldiers sustained facial injuries. Medical advances meant that more survived their wounds than ever before, yet disfigured soldiers did not receive the hero's welcome they deserved. In The Facemaker, award-winning historian Lindsey Fitzharris tells the astonishing story of the pioneering plastic surgeon Harold Gillies, who dedicated himself to restoring the faces - and the identities - of a brutalized generation. Gillies, a Cambridge-educated New Zealander, became interested in the nascent field of plastic surgery after encountering the human wreckage on the front. Returning to Britain, he established one of the world's first hospitals dedicated entirely to facial reconstruction in Sidcup, south-east England. There, Gillies assembled a unique group of doctors, nurses and artists whose task was to recreate what had been torn apart. At a time when losing a limb made a soldier a hero, but losing a face made him a monster to a society largely intolerant of disfigurement, Gillies restored not just the faces of the wounded but also their spirits. Meticulously researched and grippingly told, The Facemaker places Gillies's ingenious surgical innovations alongside the poignant stories of soldiers whose lives were wrecked and repaired. The result is a vivid account of how medicine and art can merge, and of what courage and imagination can accomplish in the presence of relentless horror.