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AN INSTANT NEW YORK TIMES BESTSELLER • A BEST BOOK OF THE YEAR BY THE WASHINGTON POST • LONGLISTED FOR THE PEN E.O. WILSON LITERARY SCIENCE WRITING AWARD"Glorious. . .You will marvel at the brilliance and vast weirdness of your design." —The Washington PostBill Bryson, bestselling author of A Short History of Nearly Everything, takes us on a head-to-toe tour of the marvel that is the human body. As addictive as it is comprehensive, this is Bryson at his very best, a must-read owner's manual for everybody.Bill Bryson once again proves himself to be an incomparable companion as he guides us through the human body--how it functions, its remarkable ability to heal itself, and (unfortunately) the ways it can fail. Full of extraordinary facts (your body made a million red blood cells since you started reading this) and irresistible Bryson-esque anecdotes, The Body will lead you to a deeper understanding of the miracle that is life in general and you in particular. As Bill Bryson writes, "We pass our existence within this wobble of flesh and yet take it almost entirely for granted." The Body will cure that indifference with generous doses of wondrous, compulsively readable facts and information.

While it may seem that debates over euthanasia began with Jack Kervorkian, the practice of mercy killing extends back to Ancient Greece and beyond. In America, the debate has raged for well over a century. Now, in A Merciful End, Ian Dowbiggin offers the first full-scale historical account of one of the most controversial reform movements in America. Drawing on unprecedented access to the archives of the Euthanasia Society of America, interviews with important figures in the movement today, and flashpoint cases such as the tragic fate of Karen Ann Quinlan, Dowbiggin tells the dramatic story of the men and women who struggled throughout the twentieth century to change the nation's attitude--and its laws--regarding mercy killing. In tracing the history of the euthanasia movement, he documents its intersection with other progressive social causes: women's suffrage, birth control, abortion rights, as well as its uneasy pre-WWII alliance with eugenics. Such links brought euthanasia activists into fierce conflict with Judeo-Christian institutions who worried that "the right to die" might become a "duty to die." Indeed, Dowbiggin argues that by joining a sometimes overzealous quest to maximize human freedom with a desire to "improve" society, the euthanasia movement has been dogged by the fear that mercy killing could be extended to persons with disabilities, handicapped newborns, unconscious geriatric patients, lifelong criminals, and even the poor. Justified or not, such fears have stalled the movement, as more and more Americans now prefer better end-of-life care than wholesale changes in euthanasia laws. For anyone trying to decide whether euthanasia offers a humane alternative to prolonged suffering or violates the "sanctity of life," A Merciful End provides fascinating and much-needed historical context.

The inspiration for the PBS series Mysterious of Mental Illness, Shrinks brilliantly tells the "astonishing" story of psychiatry's origins, demise, and redemption (Siddhartha Mukherjee).Psychiatry has come a long way since the days of chaining "lunatics" in cold cells and parading them as freakish marvels before a gaping public.But, as Jeffrey Lieberman, MD, the former president of the American Psychiatric Association, reveals in his extraordinary and eye-opening book, the path to legitimacy for "the black sheep of medicine" has been anything but smooth.In Shrinks, Dr. Lieberman traces the field from its birth as a mystic pseudo-science through its adolescence as a cult of "shrinks" to its late blooming maturity — beginning after World War II — as a science-driven profession that saves lives. With fascinating case studies and portraits of the luminaries of the field — from Sigmund Freud to Eric Kandel — Shrinks is a gripping and illuminating read, and an urgent call-to-arms to dispel the stigma of mental illnesses by treating them as diseases rather than unfortunate states of mind.“A lucid popular history...At once skeptical and triumphalist. It shows just how far psychiatry has come.” —Julia M. Klein, Boston Globe

Gold Award Winner, 2024 Nonfiction Book Awards Runner-up, 2024 History category, San Francisco Book Festival Runner-up, 2024 General Non-Fiction, New York Book Festival For much of recorded history, people considered the heart to be the most important organ in the body. In cultures around the world, the heart—not the brain—was believed to be the location of intelligence, memory, emotion, and the soul. Over time, views on the purpose of the heart have transformed as people sought to understand the life forces it contains. Modern medicine and science dismissed what was once the king of the organs as a mere blood pump subservient to the brain, yet the heart remains a potent symbol of love and health and an important part of our cultural iconography. This book traces the evolution of our understanding of the heart from the dawn of civilization to the present. Vincent M. Figueredo—an accomplished cardiologist and expert on the history of the human heart—explores the role and significance of the heart in art, culture, religion, philosophy, and science across time and place. He examines how the heart really works, its many meanings in our emotional and daily lives, and what cutting-edge science is teaching us about this remarkable organ. Figueredo considers the science of heart disease, recent advancements in heart therapies, and what the future may hold. He highlights the emerging field of neurocardiology, which has found evidence of a “heart-brain connection” in mental and physical health, suggesting that ancient views hold more truth than moderns suspect. Ranging widely and deeply throughout human history, this book sheds new light on why the heart remains so central to our sense of self.

The real crisis in medicine today is not about economics, insurance, or managed care--it's about the loss of the fundamental human relationship between doctor and patient. In this wise and passionate book, one of our most eminent physicians reacquaints us with a classic notion often overlooked in modern medicine: health care with a human face, in which the time-honored art of healing guides doctors in their approach to patient care and their use of medical technology.Drawing on four decades of practice as a cardiologist and a vast knowledge of literature and medical history, Dr. Lown probes the heart and soul of the doctor-patient relationship. Insightful and accessible to all, The Lost Art of Healing describes how true healers use sympathetic listening and touch to hone their diagnostic skills, how language affects the perception of illness, how doctors and patients can cultivate a relationship of trust, and how patients can obtain the most complete and beneficial care through a combination of healing techniques and conventional practices.As Dr. Lown explains, the art of healing does not mean abandoning the spectacular advances of modern science, but rather incorporating them into a sensitive, humane, enlightened approach to medical care. With its urgent message and poignant, fascinating vignettes, The Lost Art of Healing is a book of vital, universal importance.

A New York Times 2016 Notable Book The definitive history of the successful battle to halt the AIDS epidemic--from the creator of, and inspired by, the seminal documentary How to Survive a Plague. A riveting, powerful telling of the story of the grassroots movement of activists, many of them in a life-or-death struggle, who seized upon scientific research to help develop the drugs that turned HIV from a mostly fatal infection to a manageable disease. Ignored by public officials, religious leaders, and the nation at large, and confronted with shame and hatred, this small group of men and women chose to fight for their right to live by educating themselves and demanding to become full partners in the race for effective treatments. Around the globe, 16 million people are alive today thanks to their efforts. Not since the publication of Randy Shilts's classic And the Band Played On has a book measured the AIDS plague in such brutally human, intimate, and soaring terms. In dramatic fashion, we witness the founding of ACT UP and TAG (Treatment Action Group), and the rise of an underground drug market in opposition to the prohibitively expensive (and sometimes toxic) AZT. We watch as these activists learn to become their own researchers, lobbyists, drug smugglers, and clinicians, establishing their own newspapers, research journals, and laboratories, and as they go on to force reform in the nation's disease-fighting agencies. With his unparalleled access to this community David France illuminates the lives of extraordinary characters, including the closeted Wall Street trader-turned-activist, the high school dropout who found purpose battling pharmaceutical giants in New York, the South African physician who helped establish the first officially recognized buyers' club at the height of the epidemic, and the public relations executive fighting to save his own life for the sake of his young daughter. Expansive yet richly detailed, this is an insider's account of a pivotal moment in the history of American civil rights. Powerful, heart-wrenching, and finally exhilarating, How to Survive a Plague is destined to become an essential part of the literature of AIDS.

NPR Best Book of 2019 A bioethicist’s eloquent and riveting memoir of opioid dependence and withdrawal—a harrowing personal reckoning and clarion call for change not only for government but medicine itself, revealing the lack of crucial resources and structures to handle this insidious nationwide epidemic. Travis Rieder’s terrifying journey down the rabbit hole of opioid dependence began with a motorcycle accident in 2015. Enduring half a dozen surgeries, the drugs he received were both miraculous and essential to his recovery. But his most profound suffering came several months later when he went into acute opioid withdrawal while following his physician’s orders. Over the course of four excruciating weeks, Rieder learned what it means to be “dope sick”—the physical and mental agony caused by opioid dependence. Clueless how to manage his opioid taper, Travis’s doctors suggested he go back on the drugs and try again later. Yet returning to pills out of fear of withdrawal is one route to full-blown addiction. Instead, Rieder continued the painful process of weaning himself. Rieder’s experience exposes a dark secret of American pain management: a healthcare system so conflicted about opioids, and so inept at managing them, that the crisis currently facing us is both unsurprising and inevitable. As he recounts his story, Rieder provides a fascinating look at the history of these drugs first invented in the 1800s, changing attitudes about pain management over the following decades, and the implementation of the pain scale at the beginning of the twenty-first century. He explores both the science of addiction and the systemic and cultural barriers we must overcome if we are to address the problem effectively in the contemporary American healthcare system. In Pain is not only a gripping personal account of dependence, but a groundbreaking exploration of the intractable causes of America’s opioid problem and their implications for resolving the crisis. Rieder makes clear that the opioid crisis exists against a backdrop of real, debilitating pain—and that anyone can fall victim to this epidemic.

The extraordinary story of an unjustly forgotten group of Black men in Pittsburgh who became the first paramedics in America, saving lives and changing the course of emergency medicine around the world. Until the 1970s, if you suffered a medical crisis, your chances of survival were minimal. A 9-1-1 call might bring police or even the local funeral home. But that all changed with Freedom House EMS in Pittsburgh, a group of Black men who became America's first paramedics and set the gold standard for emergency medicine around the world, only to have their story and their legacy erased--until now. In American Sirens, acclaimed journalist and paramedic Kevin Hazzard tells the dramatic story of how a group of young, undereducated Black men forged a new frontier of healthcare. He follows a rich cast of characters that includes John Moon, an orphan who found his calling as a paramedic; Peter Safar, the Nobel Prize-nominated physician who invented CPR and realized his vision for a trained ambulance service; and Nancy Caroline, the idealistic young doctor who turned a scrappy team into an international leader. At every turn, Freedom House battled racism--from the community, the police, and the government. Their job was grueling, the rules made up as they went along, their mandate nearly impossible--and yet despite the long odds and fierce opposition, they succeeded spectacularly. Never-before revealed in full, this is a rich and troubling hidden history of the Black origins of America's paramedics, a special band of dedicated essential workers, who stand ready to serve day and night on the line between life and death for every one of us.

What happens to us as we die? Discover the answers in this exclusive 25th anniversary edition of Sherwin B Nuland's seminal book With a foreword by Paul Kalanithi, bestselling author of When Breath Becomes Air. There are many books intended to help people deal with the trauma of bereavement, but few which explore the reality of death itself. Sherwin B. Nuland - with over thirty years' experience as a surgeon - explains in detail the processes which take place in the body and strips away many illusions about death. The result is a unique and compelling book, addressing the one final fact that all of us must confront. 'I don't know of any writer or scientist who has shown us the face of death as clearly, honestly and compassionately as Sherwin Nuland does here' James Gleick, author of Chaos