Empfehlungen basierend auf "The Blue Zones: Lessons for Living Longer From the People Who've Lived the Longest"

A riveting medical mystery about a young woman’s quest to uncover the truth about her likely fatal genetic disorder that opens a window onto the exploding field of genomic medicine When Joselin Linder was in her twenties her legs suddenly started to swell. After years of misdiagnoses, doctors discovered a deadly blockage in her liver. Struggling to find  an explanation for her unusual condition, Joselin compared the medical chart of her father—who had died from a mysterious disease, ten years prior—with that of an uncle who had died under similarly strange circumstances. Delving further into the past, she discovered that her great-grandmother had displayed symptoms similar to hers before her death. Clearly, this was more than a fluke. Setting out to build a more complete picture of the illness that haunted her family, Joselin approached Dr. Christine Seidman, the head of a group of world-class genetic researchers at Harvard Medical School, for help. Dr. Seidman had been working on her family’s case for twenty years and had finally confirmed that fourteen of Joselin’s relatives carried something called a private mutation—meaning that they were the first known people to experience the baffling symptoms of a brand new genetic mutation. Here, Joselin tells the story of their gene: the lives it claimed and the future of genomic medicine with the potential to save those that remain.  Digging into family records and medical history, conducting interviews with relatives and friends, and reflecting on her own experiences with the Harvard doctor, Joselin pieces together the lineage of this deadly gene to write a gripping and unforgettable exploration of family, history, and love. A compelling chronicle of survival and perseverance, The Family Gene is an important story of a young woman reckoning with her father’s death, her own mortality, and her ethical obligations to herself and those closest to her.

Journalist Beth Macy's definitive account of America's opioid epidemic "masterfully interlaces stories of communities in crisis with dark histories of corporate greed and regulatory indifference" (New York Times) -- from the boardroom to the courtroom and into the living rooms of Americans.In this extraordinary work, Beth Macy takes us into the epicenter of a national drama that has unfolded over two decades. From the labs and marketing departments of big pharma to local doctor's offices; wealthy suburbs to distressed small communities in Central Appalachia; from distant cities to once-idyllic farm towns; the spread of opioid addiction follows a tortuous trajectory that illustrates how this crisis has persisted for so long and become so firmly entrenched.Beginning with a single dealer who lands in a small Virginia town and sets about turning high school football stars into heroin overdose statistics, Macy sets out to answer a grieving mother's question-why her only son died-and comes away with a gripping, unputdownable story of greed and need. From the introduction of OxyContin in 1996, Macy investigates the powerful forces that led America's doctors and patients to embrace a medical culture where overtreatment with painkillers became the norm. In some of the same communities featured in her bestselling book Factory Man, the unemployed use painkillers both to numb the pain of joblessness and pay their bills, while privileged teens trade pills in cul-de-sacs, and even high school standouts fall prey to prostitution, jail, and death.Through unsparing, compelling, and unforgettably humane portraits of families and first responders determined to ameliorate this epidemic, each facet of the crisis comes into focus. In these politically fragmented times, Beth Macy shows that one thing uniting Americans across geographic, partisan, and class lines is opioid drug abuse. But even in the midst of twin crises in drug abuse and healthcare, Macy finds reason to hope and ample signs of the spirit and tenacity that are helping the countless ordinary people ensnared by addiction build a better future for themselves, their families, and their communities."An impressive feat of journalism, monumental in scope and urgent in its implications." -- Jennifer Latson, The Boston Globe

The story of one man's evolution from naïve and ambitious young intern to world-class neurosurgeon.With poignant insight and humor, Frank Vertosick Jr., MD, describes some of the greatest challenges of his career, including a six-week-old infant with a tumor in her brain, a young man struck down in his prime by paraplegia, and a minister with a .22-caliber bullet lodged in his skull. Told through intimate portraits of Vertosick’s patients and unsparing yet fascinatingly detailed descriptions of surgical procedures, When the Air Hits Your Brain―the culmination of decades spent struggling to learn an unforgiving craft―illuminates both the mysteries of the mind and the realities of the operating room.

It's a fact of DNA: If you can trace your roots back to Africa, Asia, the Caribbean, India, Latin America, the Mediterranean, the Middle East, the South Pacific, or any group of Native Americans, your genes react similarly to genes in the darkest skin. And chances are, you may have received confusing advice -- or no advice at all -- about how to care for your skin. Although nearly half the population of the United States shares the hallmarks of skin of color, many dermatologists and beauty consultants routinely prescribe remedies created for Caucasian skin without understanding how sensitive and easily damaged skin of color is. It's no wonder, then, that many women and men of color continually battle skin problems, and it takes a terrible toll on their self-esteem.Finally, Beautiful Skin of Color unlocks the particular secrets of your skin and provides the answers you've been searching for. Dr. Fran Cook-Bolden and Dr. Jeanine Downie, internationally recognized dermatologists and women of color, and Barbara Nevins Taylor, an award-winning reporter on skin and hair issues, offer clear, specific advice to help you achieve and maintain a healthy, gorgeous complexion.In a quick-reference, A-to-Z format, using examples drawn from personal and professional experience, Dr. Cook-Bolden and Dr. Downie explain why problems occur, and then prescribe reliable remedies and groundbreaking new procedures specifically created for skin of color.Throughout this comprehensive guide, the doctors show you how to work with your skin and hair -- and your dermatologist -- to create your own unique skin-management program. A long-overdue and much-needed resource, Beautiful Skin of Color is certain to help you look and feel your best.

Sleep is one of the most important aspects of our life, health and longevity and yet it is increasingly neglected in twenty-first-century society, with devastating consequences: every major disease in the developed world - Alzheimer's, cancer, obesity, diabetes - has very strong causal links to deficient sleep.Until very recently, science had no answer to the question of why we sleep, or what good it served, or why its absence is so damaging to our health. Compared to the other basic drives in life - eating, drinking, and reproducing - the purpose of sleep remained elusive.Now, in this book, the first of its kind written by a scientific expert, Professor Matthew Walker explores twenty years of cutting-edge research to solve the mystery of why sleep matters. Looking at creatures from across the animal kingdom as well as major human studies, Why We Sleep delves in to everything from what really happens during REM sleep to how caffeine and alcohol affect sleep and why our sleep patterns change across a lifetime, transforming our appreciation of the extraordinary phenomenon that safeguards our existence.

For nearly 40 years, Rosen’s Emergency Medicine has provided emergency physicians, residents, physician assistants, and other emergency medicine practitioners with authoritative, accessible, and comprehensive information in this rapidly evolving field. The fully revised 10th Edition delivers practical, evidence-based knowledge and specific recommendations from clinical experts in a clear, precise format, with focused writing, current references, and extensive use of illustrations to provide definitive guidance for emergency conditions. With coverage ranging from airway management and critical care through diagnosis and treatment of virtually every emergency condition, from highly complex to simple and common, this award-winning, two-volume reference remains your #1 choice for reliable, up-to-date information across the entire spectrum of emergency medicine practice. Offers the most immediately clinically relevant content of any emergency medicine resource, providing diagnostic and treatment recommendations and workflows with clear indications and preferred actions.  Contains eight entirely new chapters covering coronaviruses/COVID-19, the morbidly obese patient, human trafficking, sexual minority (LGBTQ) patients, social determinants of health, community violence, and humanitarian aid in war and crisis.   Features over 1,700 figures, including more than 350 new anatomy drawings, graphs and charts, algorithms, and photos.  Includes new information across the spectrum of emergency care, such as adult and pediatric airway management, shock, pandemic disease, emergency toxicology, sepsis syndrome, resuscitation, medical emergencies of pregnancy, the immunocompromised patient, child abuse, pediatric sedation, pediatric trauma, and more.  Features revised and refined chapter templates that enhance navigation, making it easy to find key information quickly.  Provides access to more than 1,200 questions and answers online to aid in exam preparation, as well as two dozen new video clips showing how to best perform critical emergency procedures in real time.  Reviewed and verified cover-to-cover by a team of expert clinical pharmacists to ensure accuracy and completeness of all drug information and treatment recommendations. 

A candid, feminist, and personal deep dive into the science and culture of pregnancy and motherhoodLike most first-time mothers, Angela Garbes was filled with questions when she became pregnant. What exactly is a placenta and how does it function? How does a body go into labor? Why is breast best? Is wine totally off-limits? But as she soon discovered, it’s not easy to find satisfying answers. Your obstetrician will cautiously quote statistics; online sources will scare you with conflicting and often inaccurate data; and even the most trusted books will offer information with a heavy dose of judgment. To educate herself, the food and culture writer embarked on an intensive journey of exploration, diving into the scientific mysteries and cultural attitudes that surround motherhood to find answers to questions that had only previously been given in the form of advice about what women ought to do—rather than allowing them the freedom to choose the right path for themselves.In Like a Mother, Garbes offers a rigorously researched and compelling look at the physiology, biology, and psychology of pregnancy and motherhood, informed by in-depth reportage and personal experience. With the curiosity of a journalist, the perspective of a feminist, and the intimacy and urgency of a mother, she explores the emerging science behind the pressing questions women have about everything from miscarriage to complicated labors to postpartum changes. The result is a visceral, full-frontal look at what’s really happening during those nine life-altering months, and why women deserve access to better care, support, and information.Infused with humor and born out of awe, appreciation, and understanding of the female body and its strength, Like a Mother debunks common myths and dated assumptions, offering guidance and camaraderie to women navigating one of the biggest and most profound changes in their lives.

WINNER OF THE PULITZER PRIZE • Winner of The New York Public Library’s Helen Bernstein Book Award • “A new classic of science reporting.”—The New York TimesThe riveting true story of a small town ravaged by industrial pollution, Toms River melds hard-hitting investigative reporting, a fascinating scientific detective story, and an unforgettable cast of characters into a sweeping narrative in the tradition of A Civil Action, The Emperor of All Maladies, and The Immortal Life of Henrietta Lacks.One of New Jersey’s seemingly innumerable quiet seaside towns, Toms River became the unlikely setting for a decades-long drama that culminated in 2001 with one of the largest legal settlements in the annals of toxic dumping. A town that would rather have been known for its Little League World Series champions ended up making history for an entirely different reason: a notorious cluster of childhood cancers scientifically linked to local air and water pollution. For years, large chemical companies had been using Toms River as their private dumping ground, burying tens of thousands of leaky drums in open pits and discharging billions of gallons of acid-laced wastewater into the town’s namesake river.In an astonishing feat of investigative reporting, prize-winning journalist Dan Fagin recounts the sixty-year saga of rampant pollution and inadequate oversight that made Toms River a cautionary example for fast-growing industrial towns from South Jersey to South China. He tells the stories of the pioneering scientists and physicians who first identified pollutants as a cause of cancer, and brings to life the everyday heroes in Toms River who struggled for justice: a young boy whose cherubic smile belied the fast-growing tumors that had decimated his body from birth; a nurse who fought to bring the alarming incidence of childhood cancers to the attention of authorities who didn’t want to listen; and a mother whose love for her stricken child transformed her into a tenacious advocate for change.A gripping human drama rooted in a centuries-old scientific quest, Toms River is a tale of dumpers at midnight and deceptions in broad daylight, of corporate avarice and government neglect, and of a few brave individuals who refused to keep silent until the truth was exposed.NAMED ONE OF THE BEST BOOKS OF THE YEAR BY NPR AND KIRKUS REVIEWS“A thrilling journey full of twists and turns, Toms River is essential reading for our times. Dan Fagin handles topics of great complexity with the dexterity of a scholar, the honesty of a journalist, and the dramatic skill of a novelist.”—Siddhartha Mukherjee, M.D., author of the Pulitzer Prize–winning The Emperor of All Maladies“A complex tale of powerful industry, local politics, water rights, epidemiology, public health and cancer in a gripping, page-turning environmental thriller.”—NPR“Unstoppable reading.”—The Philadelphia Inquirer“Meticulously researched and compellingly recounted . . . It’s every bit as important—and as well-written—as A Civil Action and The Immortal Life of Henrietta Lacks.”—The Star-Ledger“Fascinating . . . a gripping environmental thriller.”—Kirkus Reviews (starred review)“An honest, thoroughly researched, intelligently written book.”—Slate“[A] hard-hitting account . . . a triumph.”—Nature“Absorbing and thoughtful.”—USA Today

A NEW YORK TIMES BESTSELLER * New York Times Notable Book * Best Book of the Year: New York Public Library, Kirkus Reviews, Science FridayWith a new postscript by the authorFrom an award-winning journalist, an explosive narrative investigation of the generic drug boom that reveals fraud and life-threatening dangers on a global scale—The Jungle for pharmaceuticalsMany have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.

Psycho-Oncology was the first comprehensive text in the field of psychosocial oncology and remains the gold standard today. Written by 67 internationally known psychiatry and palliative care experts, the resource is truly an essential reference for all providers of palliative care.Joining Oxford Medicine Online this resource offers the best quality content in an easy-to-access format. Online only benefits include downloading images and figures to PowerPoint and downloading chapters to PDF.