Tens of millions of people around the world are dead. Half of China is a nuclear wasteland. Mysterious flesh-eating spiders are marching through Los Angeles, Oslo, Delhi, Rio de Janeiro, and countless other cities. According to scientist Melanie Guyer, however, the spider situation seems to be looking up. Yet in Japan, a giant, truck-sized, glowing egg sack gives a shocking preview of what is to come, even as survivors in Los Angeles panic and break the quarantine zone. Out in the desert, survivalists Gordo and Shotgun are trying to invent a spider super weapon, but it’s not clear if it’s too late, because President Stephanie Pilgrim has been forced to enact the plan of last resort: The Spanish Protocol. America, you are on your own.