Empfehlungen basierend auf "Patient Zero and the Making of the AIDS Epidemic"

The bestselling author of Grain Brain uncovers the powerful role of gut bacteria in determining your brain's destiny.Debilitating brain disorders are on the rise-from children diagnosed with autism and ADHD to adults developing dementia at younger ages than ever before. But a medical revolution is underway that can solve this problem: Astonishing new research is revealing that the health of your brain is, to an extraordinary degree, dictated by the state of your microbiome - the vast population of organisms that live in your body and outnumber your own cells ten to one. What's taking place in your intestines today is determining your risk for any number of brain-related conditions.In Brain Maker, Dr. Perlmutter explains the potent interplay between intestinal microbes and the brain, describing how the microbiome develops from birth and evolves based on lifestyle choices, how it can become "sick," and how nurturing gut health through a few easy strategies can alter your brain's destiny for the better. With simple dietary recommendations and a highly practical program of six steps to improving gut ecology, Brain Maker opens the door to unprecedented brain health potential.

"Utterly fascinating." —Bill Bryson"An incredible journey." —Siddhartha MukherjeeA groundbreaking exploration of the science of longevity and mortality—from Nobel Prize-winning molecular biologist Venki RamakrishnanThe knowledge of death is so terrifying that we live most of our lives in denial of it. One of the most difficult moments of childhood must be when each of us first realizes that not only we but all our loved ones will die—and there is nothing we can do about it.Or at least, there hasn’t been. Today, we are living through a revolution in biology. Giant strides are being made in understanding why we age—and why some species live longer than others. Could we eventually cheat disease and death and live for a very long time, possibly many times our current lifespan?Venki Ramakrishnan, recipient of the Nobel Prize in Chemistry and former president of the Royal Society, takes us on a riveting journey to the frontiers of biology, asking whether we must be mortal. Covering the recent breakthroughs in scientific research, he examines the cutting edge of efforts to extend lifespan by altering our physiology. But might death serve a necessary biological purpose? What are the social and ethical costs of attempting to live forever?Why We Die is a narrative of uncommon insight and beauty from one of our leading public intellectuals.

SHORTLISTED FOR THE COSTA BIOGRAPHY PRIZETHE SUNDAY TIMES NO.2 BESTSELLERWINNER OF THE BMA PRESIDENT S AWARD 2017An incredible memoir from one of the world s most eminent heart surgeons, recalling some of the most remarkable and poignant cases he s worked on.Grim Reaper sits on the heart surgeon s shoulder. A slip of the hand and life ebbs away.The balance between life and death is so delicate, and the heart surgeon walks that rope between the two. In the operating room there is no time for doubt. It is flesh, blood, rib-retractors and pumping the vital organ with your bare hand to squeeze the life back into it. An off-day can have dire consequences this job has a steep learning curve, and the cost is measured in human life. Cardiac surgery is not for the faint of heart.Professor Stephen Westaby took chances and pushed the boundaries of heart surgery. He saved hundreds of lives over the course of a thirty-five year career and now, in his astounding memoir, Westaby details some of his most remarkable and poignant cases such as the baby who had suffered multiple heart attacks by six months old, a woman who lived the nightmare of locked-in syndrome, and a man whose life was powered by a battery for eight years.A powerful, important and incredibly moving book, Fragile Lives offers an exceptional insight into the exhilarating and sometimes tragic world of heart surgery, and how it feels to hold someone s life in your hands.

THE LATEST BOOK FROM THE AUTHOR OF THE SUNDAY TIMES #1 BESTSELLER FEEL BETTER IN 5'This is not a diet book. This is a whole new way of looking at what, why and how we eat and helps you design your own plan to build a better, healthier relationship with food' Fearne Cotton'A book with practical simple tips for everyone!' Tim Spector'It is a beautiful book and has so much in it to help us feel good and prioritise our happiness and health' Dr Gemma Newman'One of the most influential doctors in the country' Chris Evans_________________________________________________________________________It's more important than ever before that we get in shape, stay healthy and live well - Dr Chatterjee is back to show you how.Weight loss isn't a race. It isn't one size fits all. Drawing on twenty years of experience as a GP, Dr Rangan Chatterjee has created a conscious, long-lasting approach to weight loss that goes far beyond fad diets and helps to find the best solutions that work for you. Packed with quick and easy interventions this book will help you:1. Understand the effects of what, why, when, where and how we eat2. Discover the root cause of your weight gain3. Nourish your body without any crash diets or gruelling workouts4. Build a toolbox of techniques to help you lose weight, for goodWith Feel Great, Lose Weight you can make sustainable, medically-approved lifestyle changes and become a more energised, confident and healthy you._________________________________________________________________________'A blame-free book' Telegraph'This book is extremely practical, insightful and easy-to-follow' The Happy Pears

A candid, feminist, and personal deep dive into the science and culture of pregnancy and motherhoodLike most first-time mothers, Angela Garbes was filled with questions when she became pregnant. What exactly is a placenta and how does it function? How does a body go into labor? Why is breast best? Is wine totally off-limits? But as she soon discovered, it’s not easy to find satisfying answers. Your obstetrician will cautiously quote statistics; online sources will scare you with conflicting and often inaccurate data; and even the most trusted books will offer information with a heavy dose of judgment. To educate herself, the food and culture writer embarked on an intensive journey of exploration, diving into the scientific mysteries and cultural attitudes that surround motherhood to find answers to questions that had only previously been given in the form of advice about what women ought to do—rather than allowing them the freedom to choose the right path for themselves.In Like a Mother, Garbes offers a rigorously researched and compelling look at the physiology, biology, and psychology of pregnancy and motherhood, informed by in-depth reportage and personal experience. With the curiosity of a journalist, the perspective of a feminist, and the intimacy and urgency of a mother, she explores the emerging science behind the pressing questions women have about everything from miscarriage to complicated labors to postpartum changes. The result is a visceral, full-frontal look at what’s really happening during those nine life-altering months, and why women deserve access to better care, support, and information.Infused with humor and born out of awe, appreciation, and understanding of the female body and its strength, Like a Mother debunks common myths and dated assumptions, offering guidance and camaraderie to women navigating one of the biggest and most profound changes in their lives.

The inspiration for the PBS series Mysterious of Mental Illness, Shrinks brilliantly tells the "astonishing" story of psychiatry's origins, demise, and redemption (Siddhartha Mukherjee).Psychiatry has come a long way since the days of chaining "lunatics" in cold cells and parading them as freakish marvels before a gaping public.But, as Jeffrey Lieberman, MD, the former president of the American Psychiatric Association, reveals in his extraordinary and eye-opening book, the path to legitimacy for "the black sheep of medicine" has been anything but smooth.In Shrinks, Dr. Lieberman traces the field from its birth as a mystic pseudo-science through its adolescence as a cult of "shrinks" to its late blooming maturity — beginning after World War II — as a science-driven profession that saves lives. With fascinating case studies and portraits of the luminaries of the field — from Sigmund Freud to Eric Kandel — Shrinks is a gripping and illuminating read, and an urgent call-to-arms to dispel the stigma of mental illnesses by treating them as diseases rather than unfortunate states of mind.“A lucid popular history...At once skeptical and triumphalist. It shows just how far psychiatry has come.” —Julia M. Klein, Boston Globe

Guardian columnist Dr Ben Goldacre takes us on a hilarious, invigorating and informative journey through the bad science we're fed by the worst of the hacks and the quacks! When Dr Ben Goldacre saw someone on daytime TV dipping her feet in an 'Aqua Detox' footbath, releasing her toxins into the water and turning it brown, he thought he'd try the same at home. 'Like some kind of Johnny Ball cum Witchfinder General', using his girlfriend's Barbie doll, he gently passed an electrical current through the warm salt water. It turned brown. In his words: 'before my very eyes, the world's first Detox Barbie was sat, with her feet in a pool of brown sludge, purged of a weekend's immorality.' Dr Ben Goldacre is the author of the 'Bad Science' column in the Guardian and his book is about all the 'bad science' we are constantly bombarded with in the media and in advertising. At a time when science is used to prove everything and nothing, everyone has their own 'bad science' moments -- from the useless pie-chart on the back of cereal packets to the use of the word 'visibly' in cosmetics ads.This book will help people to quantify their instincts -- that a lot of the so-called 'science' which appears in the media and in advertising is just wrong or misleading. Satirical and amusing -- and unafraid to expose the ridiculous -- it provides the reader with the facts they need to differentiate the good from the bad. Full of spleen, this is a hilarious, invigorating and informative journey through the world of 'bad science'.

From the National Magazine Award-winning Runner’s World columnist, frequent New Yorker online contributor, and Cambridge-trained physicist: a fascinating and definitive exploration of the extraordinary science of human endurance and the secrets of human performance, for fans of The Sports Gene, Born to Run, and Grit.From running a two-hour marathon to summiting Mount Everest, we’re fascinated by the extremes of human endurance, constantly testing both our physical and psychological limits.How high or far or fast can humans go? And what about individual potential: what defines a person’s limits?For years, physiology determined the answer: heart size, lung capacity, and muscle strength. But over the past decade, a wave of dramatic findings in the cutting-edge science of endurance has completely overturned our understanding of human limitation. Endure widely disseminates these findings for the first time: It’s the brain that dictates how far we can go—which means we can always push ourselves further.Hutchinson presents an overview of science’s search for understanding human fatigue, from crude experiments with electricity and frogs’ legs to sophisticated brain imaging technology. Going beyond the traditional mechanical view of human limits (like a car with a brick on its gas pedal, we go until the tank runs out of gas), he instead argues that a key element in endurance is how the brain responds to distress signals—whether heat, or cold, or muscles screaming with lactic acid—and reveals that we can train to improve brain response.An elite distance runner himself, Hutchinson takes us to the forefront of the new sports psychology—brain electrode jolts, computer-based training, subliminal messaging—and presents startling new discoveries enhancing the performance of athletes today and shows how anyone can utilize these tactics to bolster their own performance—and get the most out of their bodies.

In This Accessible And Groundbreaking Book -- Filled With The Moving Stories Of Real People -- Medical Doctor And Bestselling Author Of Scattered Minds, Gabor Maté, Shows That Emotion And Psychological Stress Play A Powerful Role In The Onset Of Chronic Illness. Western Medicine Achieves Spectacular Triumphs When Dealing With Acute Conditions Such As Fractured Bones Or Life-threatening Infections. It Is Less Successful Against Ailments Not Susceptible To The Quick Ministrations Of Scalpel, Antibiotic Or Miracle Drug. Trained To Consider Mind And Body Separately, Physicians Are Often Helpless In Arresting The Advance Of Most Of The Chronic Diseases, Such As Breast Cancer, Rheumatoid Arthritis, Crohn’s Disease, Multiple Sclerosis, Fibromyalgia, And Even Alzheimer’s Disease. Gabor Maté Has Found That In All Of These Chronic Conditions, There Is A Common Thread: People Afflicted By These Diseases Have Led Lives Of Excessive Stress, Often Invisible To The Individuals Themselves. From An Early Age, Many Of Us Develop A Psychological Coping Style That Keeps Us Out Of Touch With The Signs Of Stress. So-called Negative Emotions, Particularly Anger, Are Suppressed. Dr. Maté Writes With Great Conviction That Knowledge Of How Stress And Disease Are Connected Is Essential To Prevent Illness In The First Place, Or To Facilitate Healing. When The Body Says No Is An Impressive Contribution To Current Research On The Physiological Connection Between Life’s Stresses And Emotions And The Body Systems Governing Nerves, Immune Apparatus And Hormones. With Great Compassion And Erudition, Gabor Maté Demystifies Medical Science And, As He Did In Scattered Minds, Invites Us All To Be Our Own Health Advocates. Excerpt From When The Body Says No “only An Intellectual Luddite Would Deny The Enormous Benefits That Have Accrued To Humankind From The Scrupulous Application Of Scientific Methods. But Not All Aspects Of Illness Can Be Reduced To Facts Verified By Double-blind Studies And By The Strictest Scientific Techniques. We Confine Ourselves To A Narrow Realm Indeed If We Exclude From Accepted Knowledge The Contributions Of Human Experience And Insight. . . . “in 1892 William Osler, One Of The Greatest Physicians Of All Time, Suspected Rheumatoid Arthritis To Be A Stress-related Disorder. Today Rheumatology All But Ignores That Wisdom, Despite The Supporting Scientific Evidence That Has Accumulated In The 110 Years Since Osler First Published His Text. That Is Where The Narrow Scientific Approach Has Brought The Practice Of Medicine. Elevating Modern Science To Be The Final Arbiter Of Our Sufferings, We Have Been Too Eager To Discard The Insights Of Previous Ages.” From The Hardcover Edition.

A NEW YORK TIMES BESTSELLER * New York Times Notable Book * Best Book of the Year: New York Public Library, Kirkus Reviews, Science FridayWith a new postscript by the authorFrom an award-winning journalist, an explosive narrative investigation of the generic drug boom that reveals fraud and life-threatening dangers on a global scale—The Jungle for pharmaceuticalsMany have hailed the widespread use of generic drugs as one of the most important public-health developments of the twenty-first century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our doctors, our pharmacists and our regulators that generic drugs are identical to their brand-name counterparts, just less expensive. But is this really true?Katherine Eban’s Bottle of Lies exposes the deceit behind generic-drug manufacturing—and the attendant risks for global health. Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings?A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.