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It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan?In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.”This book takes us to the frontlines of research many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it.

The bestselling author of Grain Brain uncovers the powerful role of gut bacteria in determining your brain's destiny.Debilitating brain disorders are on the rise-from children diagnosed with autism and ADHD to adults developing dementia at younger ages than ever before. But a medical revolution is underway that can solve this problem: Astonishing new research is revealing that the health of your brain is, to an extraordinary degree, dictated by the state of your microbiome - the vast population of organisms that live in your body and outnumber your own cells ten to one. What's taking place in your intestines today is determining your risk for any number of brain-related conditions.In Brain Maker, Dr. Perlmutter explains the potent interplay between intestinal microbes and the brain, describing how the microbiome develops from birth and evolves based on lifestyle choices, how it can become "sick," and how nurturing gut health through a few easy strategies can alter your brain's destiny for the better. With simple dietary recommendations and a highly practical program of six steps to improving gut ecology, Brain Maker opens the door to unprecedented brain health potential.

Paperback. Pub Date :2014-01-02 Pages: 336 Language: English Publisher: HarperCollins UK Sugar is toxic. addictive and everywhere So what chance do you have of living sugar-freeWith busy lives and little time left for cooking we find ourselves. relying on a diet of processed food But this is what's responsible for our chronically expanding waistlines. soaring levels of diabetes and a catalogue of diseases.Dr Robert Lustig reveals the truth about our sugar-laden food:. Why conventional low-fat weight loss advice won't work: not every calorie is the same. and skipping lunch doesn't mean it's ok to eat dessert Why too much sugar can cause serious illness even if you are not overweight How the food industry is filling our diets with hidden sugars - and which foods you must cut out to avoid themHow governments are complacent about. and even complicit in. exacerbating our food deb...

From the National Magazine Award-winning Runner’s World columnist, frequent New Yorker online contributor, and Cambridge-trained physicist: a fascinating and definitive exploration of the extraordinary science of human endurance and the secrets of human performance, for fans of The Sports Gene, Born to Run, and Grit.From running a two-hour marathon to summiting Mount Everest, we’re fascinated by the extremes of human endurance, constantly testing both our physical and psychological limits.How high or far or fast can humans go? And what about individual potential: what defines a person’s limits?For years, physiology determined the answer: heart size, lung capacity, and muscle strength. But over the past decade, a wave of dramatic findings in the cutting-edge science of endurance has completely overturned our understanding of human limitation. Endure widely disseminates these findings for the first time: It’s the brain that dictates how far we can go—which means we can always push ourselves further.Hutchinson presents an overview of science’s search for understanding human fatigue, from crude experiments with electricity and frogs’ legs to sophisticated brain imaging technology. Going beyond the traditional mechanical view of human limits (like a car with a brick on its gas pedal, we go until the tank runs out of gas), he instead argues that a key element in endurance is how the brain responds to distress signals—whether heat, or cold, or muscles screaming with lactic acid—and reveals that we can train to improve brain response.An elite distance runner himself, Hutchinson takes us to the forefront of the new sports psychology—brain electrode jolts, computer-based training, subliminal messaging—and presents startling new discoveries enhancing the performance of athletes today and shows how anyone can utilize these tactics to bolster their own performance—and get the most out of their bodies.

Gold Award Winner, 2024 Nonfiction Book Awards Runner-up, 2024 History category, San Francisco Book Festival Runner-up, 2024 General Non-Fiction, New York Book Festival For much of recorded history, people considered the heart to be the most important organ in the body. In cultures around the world, the heart—not the brain—was believed to be the location of intelligence, memory, emotion, and the soul. Over time, views on the purpose of the heart have transformed as people sought to understand the life forces it contains. Modern medicine and science dismissed what was once the king of the organs as a mere blood pump subservient to the brain, yet the heart remains a potent symbol of love and health and an important part of our cultural iconography. This book traces the evolution of our understanding of the heart from the dawn of civilization to the present. Vincent M. Figueredo—an accomplished cardiologist and expert on the history of the human heart—explores the role and significance of the heart in art, culture, religion, philosophy, and science across time and place. He examines how the heart really works, its many meanings in our emotional and daily lives, and what cutting-edge science is teaching us about this remarkable organ. Figueredo considers the science of heart disease, recent advancements in heart therapies, and what the future may hold. He highlights the emerging field of neurocardiology, which has found evidence of a “heart-brain connection” in mental and physical health, suggesting that ancient views hold more truth than moderns suspect. Ranging widely and deeply throughout human history, this book sheds new light on why the heart remains so central to our sense of self.

From the international bestselling author of Gut, an entertaining and highly informative book about how the body's organs work in tandem to keep us as healthy as we can be. In a world that is becoming ever louder and more complex, sometimes the best perspective is to look inward--at our own physicality. For thousands of years, our bodies have faced challenges and found their own unique ways to overcome them. What can we learn from these extraordinarily complex beings? In her new book, internationally renowned medical expert and star of Netflix's Hack Your Health Giulia Enders embarks on a journey of discovery into our inner workings, raising fundamental questions: What can the immune system teach us about security? How does the process of wound-healing inform our understanding of emotional recovery? What do we truly need to thrive? What are we capable of when we achieve peak health? How do we truly want to treat one another? Our bodies offer fascinating answers to all these questions, transforming our perspective on life itself. With the latest scientific insights and her unmatched talent for making complex concepts vividly accessible, Giulia Enders inspires a deep appreciation for something that is both intimately familiar yet profoundly mysterious--the very basis for how we find our happiest selves.

Reinforce your knowledge of physiology with this active, engaging, and relaxing review method! Netter's Physiology Coloring Book makes abstract concepts more concrete as you use color and tactile movement to reinforce your memory and understanding of challenging topics. It's a fun and interactive way to learn and review a complex but fascinating subject-whether you're taking a physiology course or lab, or preparing for a career in science or medicine and healthcare. More than "just" a coloring book, this unique learning tool offers: More than 100 key topics in physiology, using bold, clear drawings based on classic artwork by Frank Netter, MD and other master scientific and medical illustrators. Coloring exercises that emphasize pathways, processes, and cycles for a visual memory aid. Quick-reference tables and Pathophysiology Notes that bridge basic science with health care and medicine. Workbook review questions and drawing challenges to reinforce comprehension and retention. Enhanced eBook version included with purchase. Your enhanced eBook includes completed coloring and workbook pages for reference and allows you to access all of the text and figures, from the book on a variety of devices.

The New York Times Bestseller from Surgeon General, Vivek H. Murthy, MD. “We have a massive, deadly epidemic hidden in plain sight: loneliness. It is as harmful to health as smoking and far more common. And as his gripping stories of the science and suffering make clear, we can do something about it. Together is fascinating, moving, and essential reading.”—Atul Gawande, author of Being Mortal “Together made me rethink much of what I believe about physical health, public policy, and the human condition. By revealing America’s epidemic of loneliness—and then offering an array of remedies for the condition—Murthy has done a great service, and made Together the most important book you’ll read this year.”—Daniel H. Pink, #1 New York Times bestselling author of When and Drive The book we need NOW to avoid a social recession, Murthy’s prescient message is about the importance of human connection, the hidden impact of loneliness on our health, and the social power of community. Humans are social creatures: In this simple and obvious fact lies both the problem and the solution to the current crisis of loneliness. In his groundbreaking book, the 19th surgeon general of the United States Dr. Vivek Murthy makes a case for loneliness as a public health concern: a root cause and contributor to many of the epidemics sweeping the world today from alcohol and drug addiction to violence to depression and anxiety. Loneliness, he argues, is affecting not only our health, but also how our children experience school, how we perform in the workplace, and the sense of division and polarization in our society. But, at the center of our loneliness is our innate desire to connect. We have evolved to participate in community, to forge lasting bonds with others, to help one another, and to share life experiences. We are, simply, better together. The lessons in Together have immediate relevance and application. These four key strategies will help us not only to weather this crisis, but also to heal our social world far into the future. Spend time each day with those you love. Devote at least 15 minutes each day to connecting with those you most care about. Focus on each other. Forget about multitasking and give the other person the gift of your full attention, making eye contact, if possible, and genuinely listening. Embrace solitude. The first step toward building stronger connections with others is to build a stronger connection with oneself. Meditation, prayer, art, music, and time spent outdoors can all be sources of solitary comfort and joy. Help and be helped. Service is a form of human connection that reminds us of our value and purpose in life. Checking on a neighbor, seeking advice, even just offering a smile to a stranger six feet away, all can make us stronger. During Murthy’s research for Together, he found that there were few issues that elicited as much enthusiastic interest from both very conservative and very liberal members of Congress, from young and old people, or from urban and rural residents alike. Loneliness was something so many people have known themselves or have seen in the people around them. In the book, Murthy also shares his own deeply personal experiences with the subject—from struggling with loneliness in school, to the devastating loss of his uncle who succumbed to his own loneliness, as well as the important example of community and connection that his parents modeled. Simply, it’s a universal condition that affects all of us directly or through the people we love—now more than ever.

Science journalist Sally Adee breaks open the field of bioelectricity—the electric currents that run through our bodies and every living thing—its misunderstood history, and why new discoveries will lead to new ways around antibiotic resistance, cleared arteries, and new ways to combat cancer. You may be familiar with the idea of our body's biome: the bacterial fauna that populate our gut and can so profoundly affect our health. In We Are Electric we cross into new scientific understanding: discovering your body's electrome. Every cell in our bodies—bones, skin, nerves, muscle—has a voltage, like a tiny battery. It is the reason our brain can send signals to the rest of our body, how we develop in the womb, and why our body knows to heal itself from injury. When bioelectricity goes awry, illness, deformity, and cancer can result. But if we can control or correct this bioelectricity, the implications for our health are remarkable: an undo switch for cancer that could flip malignant cells back into healthy ones; the ability to regenerate cells, organs, even limbs; to slow aging and so much more. The next scientific frontier might be decrypting the bioelectric code, much the way we did the genetic code. Yet the field is still emerging from two centuries of skepticism and entanglement with medical quackery, all stemming from an 18th-century scientific war about the nature of electricity between Luigi Galvani (father of bioelectricity, famous for shocking frogs) and Alessandro Volta (inventor of the battery). In We Are Electric, award-winning science writer Sally Adee takes readers through the thrilling history of bioelectricity and into the future: from the Victorian medical charlatans claiming to use electricity to cure everything from paralysis to diarrhea, to the advances helped along by the giant axons of squids, and finally to the brain implants and electric drugs that await us—and the moral implications therein.  The bioelectric revolution starts here.

Designed to provide a nonmathematical introduction to biostatistics for medical and health science students, graduate students in the biological sciences, physicians, and researchers, this text explains statistical principles in non-technical language and focuses on explaining the proper scientific interpretation of statistical tests rather than on the mathematical logic of the tests themselves. Intuitive Biostatistics covers all the topics typically found in an introductory statistics text, but with the emphasis on confidence intervals rather than P values, making it easier for students to understand both. Additionally, it introduces a broad range of topics left out of most other introductory texts but used frequently in biomedical publications, including survival curves. multiple comparisons, sensitivity and specificity of lab tests, Bayesian thinking, lod scores, and logistic, proportional hazards and nonlinear regression. By emphasizing interpretation rather than calculation, this text provides a clear and virtually painless introduction to statistical principles for those students who will need to use statistics constantly in their work. In addition, its practical approach enables readers to understand the statistical results published in biological and medical journals.