Empfehlungen basierend auf "A Man on the Moon: The Voyages of the Apollo Astronauts"

One of Scientific American's Best Staff Reads of 2023A gripping business narrative and scientific thriller about what it takes to bring a wonder drug to market―and save countless lives.For Blood and Money tells the little-known story of how an upstart biotechnology company created a one-in-a-million cancer drug, and how members of the core team―denied their share of the profits―went and did it again. In this epic saga of money and science, veteran financial journalist Nathan Vardi explains how the invention of two of the biggest cancer drugs in history became (for their backers) two of the greatest Wall Street bets of all time.In the multibillion-dollar business of biotech, where pharmaceutical companies, the government, hedge funds, and venture capitalists have spent billions on funding, experimentation, and treatments, a single molecule can stop cancer in its tracks―and make the people who find that rare molecule astonishingly rich. For Blood and Money follows a small team at a biotech start-up in California, who have found one of these rare molecules. Their compound, known as a BTK inhibitor, seems to work on a vicious type of leukemia. When patients start rising from their hospice beds, the team knows they’re onto something big.What follows is a story of genius, pathos, and drama, in which vivid characters navigate a world of corporate intrigue and ambiguous morality. Vardi’s narrative immerses readers in the recent explosion of biotech start-ups. He describes the scientists, doctors, and investors who are risking everything to develop new, life-saving treatments, and introduces suffering patients for whom the stakes are life-or-death. A gripping nonfiction read, For Blood and Money illustrates why it’s so hard to bring new drugs to market, explains why they are so expensive, and examines how profit-driven venture capitalists are shaping the future of medicine.

Few books on software project management have been as influential and timeless as The Mythical Man-Month. With a blend of software engineering facts and thought-provoking opinions, Fred Brooks offers insight for anyone managing complex projects. These essays draw from his experience as project manager for the IBM System/360 computer family and then for OS/360, its massive software system. Now, 20 years after the initial publication of his book, Brooks has revisited his original ideas and added new thoughts and advice, both for readers already familiar with his work and for readers discovering it for the first time.The added chapters contain (1) a crisp condensation of all the propositions asserted in the original book, including Brooks' central argument in The Mythical Man-Month: that large programming projects suffer management problems different from small ones due to the division of labor; that the conceptual integrity of the product is therefore critical; and that it is difficult but possible to achieve this unity; (2) Brooks' view of these propositions a generation later; (3) a reprint of his classic 1986 paper "No Silver Bullet"; and (4) today's thoughts on the 1986 assertion, "There will be no silver bullet within ten years."

From Andre Agassi, one of the most beloved athletes in history and one of the most gifted men ever to step onto a tennis court, a beautiful, haunting autobiography.Agassi’s incredibly rigorous training begins when he is just a child. By the age of thirteen, he is banished to a Florida tennis camp that feels like a prison camp. Lonely, scared, a ninth-grade dropout, he rebels in ways that will soon make him a 1980s icon. He dyes his hair, pierces his ears, dresses like a punk rocker. By the time he turns pro at sixteen, his new look promises to change tennis forever, as does his lightning-fast return.And yet, despite his raw talent, he struggles early on. We feel his confusion as he loses to the world’s best, his greater confusion as he starts to win. After stumbling in three Grand Slam finals, Agassi shocks the world, and himself, by capturing the 1992 Wimbledon. Overnight he becomes a fan favorite and a media target.Agassi brings a near-photographic memory to every pivotal match and every relationship. Never before has the inner game of tennis and the outer game of fame been so precisely limned. Alongside vivid portraits of rivals from several generations—Jimmy Connors, Pete Sampras, Roger Federer—Agassi gives unstinting accounts of his brief time with Barbra Streisand and his doomed marriage to Brooke Shields. He reveals a shattering loss of confidence. And he recounts his spectacular resurrection, a comeback climaxing with his epic run at the 1999 French Open and his march to become the oldest man ever ranked number one.In clear, taut prose, Agassi evokes his loyal brother, his wise coach, his gentle trainer, all the people who help him regain his balance and find love at last with Stefanie Graf. Inspired by her quiet strength, he fights through crippling pain from a deteriorating spine to remain a dangerous opponent in the twenty-first and final year of his career. Entering his last tournament in 2006, he’s hailed for completing a stunning metamorphosis, from nonconformist to elder statesman, from dropout to education advocate. And still he’s not done. At a U.S. Open for the ages, he makes a courageous last stand, then delivers one of the most stirring farewells ever heard in a sporting arena.With its breakneck tempo and raw candor, Open will be read and cherished for years. A treat for ardent fans, it will also captivate readers who know nothing about tennis. Like Agassi’s game, it sets a new standard for grace, style, speed, and power.

The real story of Hollywood as told by such luminaries as Steven Spielberg, Frank Capra, Katharine Hepburn, Meryl Streep, Harold Lloyd, and nearly four hundred others, assembled from the American Film Institute’s treasure trove of interviews, reveals a fresh history of the American movie industry from its beginnings to today.From the archives of the American Film Institute comes a unique picture of what it was like to work in Hollywood from its beginnings to its present day. Gleaned from nearly three thousand interviews, involving four hundred voices from the industry, Hollywood: The Oral History, lets a reader “listen in” on candid remarks from the biggest names in front of the camera—Bette Davis, Meryl Streep, Tom Hanks, Harold Lloyd—to the biggest behind it—Frank Capra, Steven Spielberg, Alfred Hitchcock, Jordan Peele, as well as the lesser known individuals that shaped what was heard and seen on screen: musicians, costumers, art directors, cinematographers, writers, sound men, editors, make-up artists, and even script timers, messengers, and publicists. The result is like a conversation among the gods and goddesses of film: lively, funny, insightful, historically accurate and, for the first time, authentically honest in its portrait of Hollywood. It’s the insider’s story.Legendary film scholar Jeanine Basinger and New York Times bestselling author Sam Wasson, both acclaimed storytellers in their own right, have undertaken the monumental task of digesting these tens of thousands of hours of talk and weaving it into a definitive portrait of workaday Hollywood.

Instant New York Times BestsellerAs the fiftieth anniversary of the first lunar landing approaches, the award winning historian and perennial New York Times bestselling author takes a fresh look at the space program, President John F. Kennedy’s inspiring challenge, and America’s race to the moon.“We choose to go to the Moon in this decade and do the other things, not because they are easy, but because they are hard; because that goal will serve to organize and measure the best of our energies and skills, because that challenge is one that we are willing to accept, one we are unwilling to postpone, and one we intend to win.”—President John F. KennedyOn May 25, 1961, JFK made an astonishing announcement: his goal of putting a man on the moon by the end of the decade. In this engrossing, fast-paced epic, Douglas Brinkley returns to the 1960s to recreate one of the most exciting and ambitious achievements in the history of humankind. American Moonshot brings together the extraordinary political, cultural, and scientific factors that fueled the birth and development of NASA and the Mercury, Gemini and Apollo projects, which shot the United States to victory in the space race against the Soviet Union at the height of the Cold War. Drawing on new primary source material and major interviews with many of the surviving figures who were key to America’s success, Brinkley brings this fascinating history to life as never before. American Moonshot is a portrait of the brilliant men and women who made this giant leap possible, the technology that enabled us to propel men beyond earth’s orbit to the moon and return them safely, and the geopolitical tensions that spurred Kennedy to commit himself fully to this audacious dream. Brinkley’s ensemble cast of New Frontier characters include rocketeer Wernher von Braun, astronaut John Glenn and space booster Lyndon Johnson.A vivid and enthralling chronicle of one of the most thrilling, hopeful, and turbulent eras in the nation’s history, American Moonshot is an homage to scientific ingenuity, human curiosity, and the boundless American spirit.

John D. Rockefeller, Sr.--history's first billionaire and the patriarch of America's most famous dynasty--is an icon whose true nature has eluded three generations of historians. Now Ron Chernow, the National Book Award-winning biographer of the Morgan and Warburg banking families, gives us a history of the mogul "etched with uncommon objectivity and literary grace . . . as detailed, balanced, and psychologically insightful a portrait of the tycoon as we may ever have" (Kirkus Reviews). Titan is the first full-length biography based on unrestricted access to Rockefeller's exceptionally rich trove of papers. A landmark publication full of startling revelations, the book will indelibly alter our image of this most enigmatic capitalist.

"One of the best baseball—and management—books out.... Deserves a place in the Baseball Hall of Fame."—Forbes Moneyball is a quest for the secret of success in baseball. Following the low-budget Oakland Athletics, their larger-than-life general manger, Billy Beane, and the strange brotherhood of amateur baseball enthusiasts, Michael Lewis has written not only "the single most influential baseball book ever" (Rob Neyer, Slate) but also what "may be the best book ever written on business" (Weekly Standard). I wrote this book because I fell in love with a story. The story concerned a small group of undervalued professional baseball players and executives, many of whom had been rejected as unfit for the big leagues, who had turned themselves into one of the most successful franchises in Major League Baseball. But the idea for the book came well before I had good reason to write it—before I had a story to fall in love with. It began, really, with an innocent question: how did one of the poorest teams in baseball, the Oakland Athletics, win so many games? With these words Michael Lewis launches us into the funniest, smartest, and most contrarian book since, well, since Liar's Poker. Moneyball is a quest for something as elusive as the Holy Grail, something that money apparently can't buy: the secret of success in baseball. The logical places to look would be the front offices of major league teams, and the dugouts, perhaps even in the minds of the players themselves. Lewis mines all these possibilities—his intimate and original portraits of big league ballplayers are alone worth the price of admission—but the real jackpot is a cache of numbers—numbers!—collected over the years by a strange brotherhood of amateur baseball enthusiasts: software engineers, statisticians, Wall Street analysts, lawyers and physics professors. What these geek numbers show—no, prove—is that the traditional yardsticks of success for players and teams are fatally flawed. Even the box score misleads us by ignoring the crucial importance of the humble base-on-balls. This information has been around for years, and nobody inside Major League Baseball paid it any mind. And then came Billy Beane, General Manager of the Oakland Athletics. Billy paid attention to those numbers —with the second lowest payroll in baseball at his disposal he had to—and this book records his astonishing experiment in finding and fielding a team that nobody else wanted. Moneyball is a roller coaster ride: before the 2002 season opens, Oakland must relinquish its three most prominent (and expensive) players, is written off by just about everyone, and then comes roaring back to challenge the American League record for consecutive wins. In a narrative full of fabulous characters and brilliant excursions into the unexpected, Michael Lewis shows us how and why the new baseball knowledge works. He also sets up a sly and hilarious morality tale: Big Money, like Goliath, is always supposed to win... how can we not cheer for David?

The gripping history of electricity and how the fateful collision of Thomas Edison, Nikola Tesla, and George Westinghouse left the world utterly transformed.In the final decades of the nineteenth century, three brilliant and visionary titans of America’s Gilded Age—Thomas Edison, Nikola Tesla, and George Westinghouse—battled bitterly as each vied to create a vast and powerful electrical empire. In Empires of Light, historian Jill Jonnes portrays this extraordinary trio and their riveting and ruthless world of cutting-edge science, invention, intrigue, money, death, and hard-eyed Wall Street millionaires. At the heart of the story are Thomas Alva Edison, the nation’s most famous and folksy inventor, creator of the incandescent light bulb and mastermind of the world’s first direct current electrical light networks; the Serbian wizard of invention Nikola Tesla, elegant, highly eccentric, a dreamer who revolutionized the generation and delivery of electricity; and the charismatic George Westinghouse, Pittsburgh inventor and tough corporate entrepreneur, an industrial idealist who in the era of gaslight imagined a world powered by cheap and plentiful electricity and worked heart and soul to create it. Edison struggled to introduce his radical new direct current (DC) technology into the hurly-burly of New York City as Tesla and Westinghouse challenged his dominance with their alternating current (AC), thus setting the stage for one of the eeriest feuds in American corporate history, the War of the Electric Currents. The battlegrounds: Wall Street, the 1893 Chicago World’s Fair, Niagara Falls, and, finally, the death chamber—Jonnes takes us on the tense walk down a prison hallway and into the sunlit room where William Kemmler, convicted ax murderer, became the first man to die in the electric chair.

No film critic has ever been as influential—or as beloved— as Roger Ebert. Over more than four decades, he built a reputation writing reviews for the Chicago Sun-Times and, later, arguing onscreen with rival Chicago Tribune critic Gene Siskel and later Richard Roeper about the movies they loved and loathed. But Ebert went well beyond a mere “thumbs up” or “thumbs down.” Readers could always sense the man behind the words, a man with interests beyond film and a lifetime’s distilled wisdom about the larger world. Although the world lost one of its most important critics far too early, Ebert lives on in the minds of moviegoers today, who continually find themselves debating what he might have thought about a current movie. The Great Movies IV is the fourth—and final—collection of Roger Ebert’s essays, comprising sixty-two reviews of films ranging from the silent era to the recent past. From films like The Cabinet of Caligari and Viridiana that have been considered canonical for decades to movies only recently recognized as masterpieces to Superman, The Big Lebowski, and Pink Floyd: The Wall, the pieces gathered here demonstrate the critical acumen seen in Ebert’s daily reviews and the more reflective and wide-ranging considerations that the longer format allowed him to offer. Ebert’s essays are joined here by an insightful foreword by film critic Matt Zoller Seitz, the current editor-in-chief of the official Roger Ebert website, and a touching introduction by Chaz Ebert. A fitting capstone to a truly remarkable career, The Great Movies IV will introduce newcomers to some of the most exceptional movies ever made, while revealing new insights to connoisseurs as well.

“A mob saga that has it all—brotherhood and betrayal, swaggering power and glittering success, and a Godfather whose reach seems utterly unrivaled. What a relentless, irresistible read.” — Don Winslow, New York Times bestselling author of The ForceA fascinating, cinematic, multigenerational history of the Cuban mob in the US from "America’s top chronicler of organized crime"* and New York Times bestselling author of Havana Nocturne.By the mid 1980s, the criminal underworld in the United States had become an ethnic polyglot; one of the most powerful illicit organizations was none other than the Cuban mob. Known on both sides of the law as "the Corporation," the Cuban mob’s power stemmed from a criminal culture embedded in south Florida’s exile community—those who had been chased from the island by Castro’s revolution and planned to overthrow the Marxist dictator and reclaim their nation.An epic story of gangsters, drugs, violence, sex, and murder rooted in the streets, The Corporation reveals how an entire generation of political exiles, refugees, racketeers, corrupt cops, hitmen, and their wives and girlfriends became caught up in an American saga of desperation and empire building. T. J. English interweaves the voices of insiders speaking openly for the first time with a trove of investigative material he has gathered over many decades to tell the story of this successful criminal enterprise, setting it against the larger backdrop of revolution, exile, and ethnicity that makes it one of the great American gangster stories that has been overlooked—until now.Drawing on the detailed reporting and impressive volume of evidence that drive his bestselling works, English offers a riveting, in-depth look at this powerful and sordid crime organization and its hold in the US.