Nebulous and unseen, existing in a state somewhere between life and death, mushi bring nothing but pain, suffering, and destruction to humans. A small community of wandering healers and naturalists known as mushishi protect humans from the ravages of these malevolent entities. Ginko, with his green eye and white hair, is a mushishi. But when Ginko tries to help a boy who seems to have found spring in the middle of winter, he and the boy both become victims of the life-sucking creatures.